ENSGALG00000004980


Gallus gallus

Features
Gene ID: ENSGALG00000004980
  
Biological name :KCNMA1
  
Synonyms : Calcium-activated potassium channel subunit alpha-1 / KCNMA1 / Q8AYS8
  
Possible biological names infered from orthology : potassium calcium-activated channel subfamily M alpha 1 / potassium large conductance calcium-activated channel, subfamily M, alpha member 1 / Q12791
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 13362771
Gene end: 13800472
  
Corresponding Affymetrix probe sets: Gga.19342.1.S1_at (Chicken Array)   Gga.19588.1.A1_at (Chicken Array)   Gga.19588.1.S1_at (Chicken Array)   Gga.3260.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040990
Ensembl peptide - ENSGALP00000059367
Ensembl peptide - ENSGALP00000063286
Ensembl peptide - ENSGALP00000062831
Ensembl peptide - ENSGALP00000060605
Ensembl peptide - ENSGALP00000060227
Ensembl peptide - ENSGALP00000007968
Ensembl peptide - ENSGALP00000039705
NCBI entrez gene - 374065     See in Manteia.
RefSeq - XM_015288191
RefSeq - XM_015288180
RefSeq - XM_015288181
RefSeq - XM_015288182
RefSeq - XM_015288183
RefSeq - XM_015288184
RefSeq - XM_015288185
RefSeq - XM_015288186
RefSeq - XM_015288187
RefSeq - XM_015288189
RefSeq - XM_015288190
RefSeq - NM_204224
RefSeq - XM_015288147
RefSeq - XM_015288148
RefSeq - XM_015288149
RefSeq - XM_015288150
RefSeq - XM_015288151
RefSeq - XM_015288152
RefSeq - XM_015288153
RefSeq - XM_015288154
RefSeq - XM_015288155
RefSeq - XM_015288156
RefSeq - XM_015288157
RefSeq - XM_015288158
RefSeq - XM_015288159
RefSeq - XM_015288160
RefSeq - XM_015288161
RefSeq - XM_015288162
RefSeq - XM_015288163
RefSeq - XM_015288164
RefSeq - XM_015288165
RefSeq - XM_015288166
RefSeq - XM_015288167
RefSeq - XM_015288168
RefSeq - XM_015288169
RefSeq - XM_015288170
RefSeq - XM_015288171
RefSeq - XM_015288172
RefSeq - XM_015288173
RefSeq - XM_015288174
RefSeq - XM_015288175
RefSeq - XM_015288176
RefSeq - XM_015288177
RefSeq - XM_015288178
RefSeq - XM_015288179
RefSeq Peptide - NP_989555
swissprot - D3X739
swissprot - A0A1L1RVH2
swissprot - A0A1L1RN69
swissprot - F1NIA4
swissprot - F1NYQ5
swissprot - A0A1L1RKS9
swissprot - Q8AYS8
swissprot - D3X747
swissprot - R4GG29
Ensembl - ENSGALG00000004980
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01092907.1ENSDARG00000110727Danio rerio
 kcnma1aENSDARG00000079840Danio rerio
 KCNMA1ENSG00000156113Homo sapiens
 Kcnma1ENSMUSG00000063142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNU1 / potassium calcium-activated channel subfamily U member 1 / A8MYU2*ENSGALG0000004566835
KCNT1 / Q8QFV0 / Potassium channel subfamily T member 1 ENSGALG0000000164518
KCNT2 / potassium sodium-activated channel subfamily T member 2 / Q6UVM3*ENSGALG0000004168017


Protein motifs (from Interpro)
Interpro ID Name
 IPR003929  Potassium channel, BK, alpha subunit
 IPR005821  Ion transport domain
 IPR016040  NAD(P)-binding domain
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0030007 cellular potassium ion homeostasis IEA
 biological_processGO:0034465 response to carbon monoxide IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045794 negative regulation of cell volume IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060073 micturition IEA
 biological_processGO:0060083 smooth muscle contraction involved in micturition IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0060072 large conductance calcium-activated potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002118 KCNMB1 / potassium calcium-activated channel subfamily M regulatory beta subunit 1 / Q16558*  / complex
 ENSGALG00000004980 KCNMA1 / Q8AYS8 / Calcium-activated potassium channel subunit alpha-1 / Q12791* / potassium calcium-activated channel subfamily M alpha 1* / potassium large conductance calcium-activated c...  / complex
 ENSGALG00000010044 KCNMB4 / potassium calcium-activated channel subfamily M regulatory beta subunit 4 / Q86W47* / Q9JIN6* / Calcium-activated potassium channel subunit beta-4 *  / complex
 ENSGALG00000031929 KCNMB2* / Q9CZM9* / Q9Y691* / AC117457.1* / Calcium-activated potassium channel subunit beta-2 * / potassium calcium-activated channel subfamily M regulatory beta subunit 2*  / complex






 

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