ENSMUSG00000063142


Mus musculus

Features
Gene ID: ENSMUSG00000063142
  
Biological name :Kcnma1
  
Synonyms : Kcnma1 / potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  
Possible biological names infered from orthology : potassium calcium-activated channel subfamily M alpha 1 / Q12791
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: A3
Gene start: 23289431
Gene end: 24014491
  
Corresponding Affymetrix probe sets: 10418053 (MoGene1.0st)   10418092 (MoGene1.0st)   1424848_at (Mouse Genome 430 2.0 Array)   1425987_a_at (Mouse Genome 430 2.0 Array)   1428948_at (Mouse Genome 430 2.0 Array)   1440728_at (Mouse Genome 430 2.0 Array)   1455554_at (Mouse Genome 430 2.0 Array)   1457018_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137141
Ensembl peptide - ENSMUSP00000136568
Ensembl peptide - ENSMUSP00000140033
Ensembl peptide - ENSMUSP00000153670
Ensembl peptide - ENSMUSP00000153584
Ensembl peptide - ENSMUSP00000153527
Ensembl peptide - ENSMUSP00000153362
Ensembl peptide - ENSMUSP00000153356
Ensembl peptide - ENSMUSP00000153316
Ensembl peptide - ENSMUSP00000153312
Ensembl peptide - ENSMUSP00000153291
Ensembl peptide - ENSMUSP00000153254
Ensembl peptide - ENSMUSP00000153247
Ensembl peptide - ENSMUSP00000153216
Ensembl peptide - ENSMUSP00000153214
Ensembl peptide - ENSMUSP00000153158
Ensembl peptide - ENSMUSP00000153083
Ensembl peptide - ENSMUSP00000153078
Ensembl peptide - ENSMUSP00000152999
Ensembl peptide - ENSMUSP00000152959
Ensembl peptide - ENSMUSP00000148692
Ensembl peptide - ENSMUSP00000141143
Ensembl peptide - ENSMUSP00000141069
Ensembl peptide - ENSMUSP00000140751
Ensembl peptide - ENSMUSP00000140275
Ensembl peptide - ENSMUSP00000140154
Ensembl peptide - ENSMUSP00000065293
Ensembl peptide - ENSMUSP00000074511
Ensembl peptide - ENSMUSP00000098393
Ensembl peptide - ENSMUSP00000108042
Ensembl peptide - ENSMUSP00000128553
Ensembl peptide - ENSMUSP00000132204
Ensembl peptide - ENSMUSP00000136447
NCBI entrez gene - 16531     See in Manteia.
MGI - MGI:99923
RefSeq - XM_017315887
RefSeq - NM_001253358
RefSeq - NM_001253359
RefSeq - NM_001253360
RefSeq - NM_001253361
RefSeq - NM_001253362
RefSeq - NM_001253363
RefSeq - NM_001253364
RefSeq - NM_001253365
RefSeq - NM_001253366
RefSeq - NM_001253367
RefSeq - NM_001253368
RefSeq - NM_001253369
RefSeq - NM_001253370
RefSeq - NM_001253371
RefSeq - NM_001253372
RefSeq - NM_001253373
RefSeq - NM_001253374
RefSeq - NM_001253375
RefSeq - NM_001253376
RefSeq - NM_001253377
RefSeq - NM_001253378
RefSeq - NM_010610
RefSeq - XM_006518591
RefSeq - XM_006518592
RefSeq - XM_006518593
RefSeq - XM_006518594
RefSeq - XM_006518595
RefSeq - XM_006518599
RefSeq - XM_006518602
RefSeq - XM_006518603
RefSeq - XM_006518605
RefSeq - XM_006518606
RefSeq - XM_006518609
RefSeq - XM_006518610
RefSeq - XM_006518613
RefSeq - XM_011244967
RefSeq - XM_017315870
RefSeq - XM_017315871
RefSeq - XM_017315872
RefSeq - XM_017315873
RefSeq - XM_017315874
RefSeq - XM_017315875
RefSeq - XM_017315876
RefSeq - XM_017315877
RefSeq - XM_017315878
RefSeq - XM_017315879
RefSeq - XM_017315880
RefSeq - XM_017315881
RefSeq - XM_017315882
RefSeq - XM_017315883
RefSeq - XM_017315884
RefSeq - XM_017315885
RefSeq - XM_017315886
RefSeq Peptide - NP_001240287
RefSeq Peptide - NP_001240288
RefSeq Peptide - NP_001240289
RefSeq Peptide - NP_001240290
RefSeq Peptide - NP_001240291
RefSeq Peptide - NP_001240292
RefSeq Peptide - NP_001240293
RefSeq Peptide - NP_001240294
RefSeq Peptide - NP_001240295
RefSeq Peptide - NP_001240296
RefSeq Peptide - NP_001240297
RefSeq Peptide - NP_001240298
RefSeq Peptide - NP_001240299
RefSeq Peptide - NP_001240300
RefSeq Peptide - NP_001240301
RefSeq Peptide - NP_001240302
RefSeq Peptide - NP_001240303
RefSeq Peptide - NP_001240304
RefSeq Peptide - NP_001240305
RefSeq Peptide - NP_001240306
RefSeq Peptide - NP_001240307
RefSeq Peptide - NP_034740
swissprot - A0A087WRS4
swissprot - A0A087WQN5
swissprot - F6V0P5
swissprot - F6WSZ3
swissprot - F6XW53
swissprot - F6ZSN2
swissprot - F7BHL0
swissprot - J3QMT8
swissprot - J3QN27
swissprot - J3QP84
swissprot - A0A087WQ41
swissprot - A0A087WQE1
swissprot - E9Q9P4
swissprot - E3VRZ4
swissprot - E3VRY9
swissprot - E3VRY6
swissprot - A0A286YE30
swissprot - A0A286YDU9
swissprot - A0A286YDR7
swissprot - A0A286YDM6
swissprot - A0A286YDC1
swissprot - A0A286YDB5
swissprot - A0A286YD59
swissprot - A0A286YD36
swissprot - A0A286YD35
swissprot - A0A286YCZ9
swissprot - A0A286YCW3
swissprot - A0A286YCQ2
swissprot - A0A286YCP1
swissprot - A0A286YCI9
swissprot - A0A286YCF5
swissprot - A0A1D5RMA3
swissprot - A0A087WSQ4
Ensembl - ENSMUSG00000063142
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01092907.1ENSDARG00000110727Danio rerio
 kcnma1aENSDARG00000079840Danio rerio
 KCNMA1ENSGALG00000004980Gallus gallus
 KCNMA1ENSG00000156113Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnu1 / A8MYU2* / potassium calcium-activated channel subfamily U member 1*ENSMUSG0000003157637
Kcnt1 / Q6ZPR4 / Potassium channel subfamily T member 1 / Q5JUK3* / potassium sodium-activated channel subfamily T member 1*ENSMUSG0000005874018
Kcnt2 / potassium sodium-activated channel subfamily T member 2 / Q6UVM3*ENSMUSG0000005272618


Protein motifs (from Interpro)
Interpro ID Name
 IPR003148  Regulator of K+ conductance, N-terminal
 IPR003929  Potassium channel, BK, alpha subunit
 IPR005821  Ion transport domain
 IPR013099  Potassium channel domain
 IPR024939  Calcium-activated potassium channel Slo-1
 IPR028325  Voltage-gated potassium channel
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0030007 cellular potassium ion homeostasis IEA
 biological_processGO:0034465 response to carbon monoxide IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045794 negative regulation of cell volume IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060073 micturition IEA
 biological_processGO:0060083 smooth muscle contraction involved in micturition IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0060072 large conductance calcium-activated potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Plscr1tm1Lex/Plscr1tm1Lex,Plscr3tm1Sims/Plscr3tm1Sims
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001396 unidirectional circling "circling behavior in one direction only, either clockwise or counterclockwise" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001407 short stride length "reduced average distance between steps" [J:34193]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001522 impaired swimming "reduced ability or inability to swim" [J:45446, J:39081]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0001731 abnormal postnatal growth "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0001994 increased blinking frequency 
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plscr1tm1Lex/Plscr1tm1Lex,Plscr3tm1Sims/Plscr3tm1Sims
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002578 impaired ability to fire action potentials "anomaly resulting in reduced changes in membrane potentials occurring in nerve or other excitable tissue when excitation occurs" [J:51377, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002807 abnormal eye blink conditioning behavior "defects in the ability of an animal to learn to blink in anticipation of an aversive stimulus (e.g., an airpuff to the eyelid) following repeated pairings with a neutral stimulus (e.g., a tone); such learning is only adaptive if the animal is able to learn the precise timing between the conditioned and unconditioned stimuli " [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002842 increased blood pressure "increased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002916 increased synaptic depression "increase in the duration of the reduction of effectiveness of synaptic connections between neurons and target after repetitive stimulation" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0003280 urinary incontinence "inability to control the urinary excretory functions" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0003484 abnormal channel response "anomalies in the electrophysiological recordings from ion channels" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Abcc6tm1Jfk/Abcc6tm1Jfk,Samd9ltm1Homy/Samd9ltm1Homy
Genetic Background: B6.129-Samd9ltm1Homy Abcc6tm1Jfk

 MP:0003868 abnormal feces composition "increase or decrease in the amount of compunds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0004037 increased muscle relaxation "greater than the normal ability of the muscle to lengthen following contractions or increase in the ability of the muscle to lengthen following contractions" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0004404 cochlear outer hair cell degeneration "degeneration or loss of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0004433 abnormal cochlear inner hair cell physiology "anomalies in processes pertinent to the function of cochlear IHCs which constitute the true sensory cell type sending impulses via the cochlear (auditory) nerve" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm1Ruth
Genetic Background: 129-Kcnma1tm1Ruth

 MP:0004597 increased susceptibility to noise-induced hearing loss "greater than normal reduction in hearing sensitivity following exposure to acute noise that is injurious to the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0004628 Dieters cell degeneration "degeneration or loss of the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0004736 abnormal distortion product otoacoustic emission "any abnormality in the sound produced by the cochlea in response to stimulation with 2 simultaneous tones of different frequencies; this measurement is particularly useful in assessing the functional state of OHCs" [eMedicine:http://www.emedicine.com/ent/topic372.htm, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm1Ruth
Genetic Background: 129-Kcnma1tm1Ruth

 MP:0004737 absent distortion product otoacoustic emissions "failure to create mechanical distortions in the inner ear when two primary tones are presented, indicating failure of outer hair cells to amplify basilar membrane motion" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0004740 sensorineural hearing loss "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0004746 abnormal cochlear IHC afferent innervation "any changes in the morphology or number of afferent terminals and/or their synapses in the cochlear IHC region" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm1Ruth
Genetic Background: 129-Kcnma1tm1Ruth

 MP:0004925 decreased susceptibility to noise-induced hearing loss "less than normal reduction in hearing sensitivity following exposure to acute noise that is injurious to the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Abcc6tm1Jfk/Abcc6tm1Jfk,Samd9ltm1Homy/Samd9ltm1Homy
Genetic Background: B6.129-Samd9ltm1Homy Abcc6tm1Jfk

 MP:0005620 abnormal muscle contractility "aberrant ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm2.1Ruth,X/Tg(Myh11-cre/ERT2)1Soff
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Postntm1Sjc/Postntm1Sjc
Genetic Background: involves: C57BL/6

 MP:0006324 abnormal cochlear nerve fiber response "anomaly in the electrophysiological recordings from a single or several auditory nerve fiber(s)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm1Ruth
Genetic Background: 129-Kcnma1tm1Ruth

 MP:0006335 abnormal hearing electrophysiology "anomaly in auditory function as it relates to electrical phenomena" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm1Ruth
Genetic Background: 129-Kcnma1tm1Ruth

 MP:0010386 abnormal urinary bladder physiology "any functional anomaly of the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm2.1Ruth,X/Tg(Myh11-cre/ERT2)1Soff
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0011535 increased urination frequency "increased frequency of urination episodes; urination at short frequent intervals occurs without an increase in daily volume of urinary output and may be caused by reduced bladder capacity or urinary tract infection" [MGI:anna]
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Allelic Composition: Bgntm1Mfy/Y,Fmodtm1Aol/Fmodtm1Aol
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Kcnma1tm1Ruth/Kcnma1tm2.1Ruth,X/Tg(Myh11-cre/ERT2)1Soff
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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