ENSGALG00000005377


Gallus gallus

Features
Gene ID: ENSGALG00000005377
  
Biological name :WWOX
  
Synonyms : WW domain-containing oxidoreductase / WWOX
  
Possible biological names infered from orthology : Q91WL8 / Q9NZC7
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 14260943
Gene end: 14381632
  
Corresponding Affymetrix probe sets: Gga.17022.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008618
NCBI entrez gene - 415801     See in Manteia.
RefSeq - NM_001030574
RefSeq Peptide - NP_001025745
swissprot - F1NXW7
Ensembl - ENSGALG00000005377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wwoxENSDARG00000007614Danio rerio
 WWOXENSG00000186153Homo sapiens
 WwoxENSMUSG00000004637Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDH14 / retinol dehydrogenase 14 / Q9ERI6* / Q9HBH5*ENSGALG0000001987328
RDH11* / RDH12* / Q96NR8* / Q9QYF1* / Q8BYK4* / Q8TC12* / Retinol dehydrogenase 11 * / Retinol dehydrogenase 12 * / retinol dehydrogenase 11 (all-trans/9-cis/11-cis)* / retinol dehydrogenas...ENSGALG0000000953828
DHRSX / dehydrogenase/reductase X-linked / Q8N5I4*ENSGALG0000001668126
DHRS13 / dehydrogenase/reductase 13 / Q5SS80* / Q6UX07* / Dehydrogenase/reductase SDR family member 13 *ENSGALG0000000400926
A0PJE2* / DHRS12* / dehydrogenase/reductase 12*ENSGALG000000403218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
Nuclear signaling by ERBB4
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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