ENSGALG00000005439


Gallus gallus

Features
Gene ID: ENSGALG00000005439
  
Biological name :ACACA
  
Synonyms : ACACA / acetyl-CoA carboxylase
  
Possible biological names infered from orthology : acetyl-CoA carboxylase alpha / acetyl-Coenzyme A carboxylase alpha / Q13085 / Q5SWU9
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 8467524
Gene end: 8567212
  
Corresponding Affymetrix probe sets: Gga.11412.1.S1_s_at (Chicken Array)   Gga.1480.1.S1_at (Chicken Array)   GgaAffx.20800.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043760
Ensembl peptide - ENSGALP00000053582
Ensembl peptide - ENSGALP00000050259
Ensembl peptide - ENSGALP00000034072
NCBI entrez gene - 396504     See in Manteia.
RefSeq - XM_015295697
RefSeq - XM_015295691
RefSeq - XM_015295692
RefSeq - XM_015295694
RefSeq - XM_015295695
RefSeq - XM_015295696
RefSeq - NM_205505
RefSeq Peptide - NP_990836
swissprot - A0A1D5PL68
swissprot - A0A1D5PBX7
swissprot - F1NWT0
swissprot - A0A1D5NTV3
Ensembl - ENSGALG00000005439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acacaENSDARG00000078512Danio rerio
 ACACAENSG00000278540Homo sapiens
 AcacaENSMUSG00000020532Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACACB* / E9Q4Z2* / O00763* / acetyl-CoA carboxylase beta* / acetyl-Coenzyme A carboxylase beta*ENSGALG0000000504374


Protein motifs (from Interpro)
Interpro ID Name
 IPR000089  Biotin/lipoyl attachment
 IPR001882  Biotin-binding site
 IPR005479  Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
 IPR005481  Biotin carboxylase-like, N-terminal domain
 IPR005482  Biotin carboxylase, C-terminal
 IPR011053  Single hybrid motif
 IPR011054  Rudiment single hybrid motif
 IPR011761  ATP-grasp fold
 IPR011762  Acetyl-coenzyme A carboxyltransferase, N-terminal
 IPR011763  Acetyl-coenzyme A carboxyltransferase, C-terminal
 IPR011764  Biotin carboxylation domain
 IPR013537  Acetyl-CoA carboxylase, central domain
 IPR013815  ATP-grasp fold, subdomain 1
 IPR016185  Pre-ATP-grasp domain superfamily
 IPR029045  ClpP/crotonase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001894 tissue homeostasis IEA
 biological_processGO:0006084 acetyl-CoA metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055088 lipid homeostasis IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003989 acetyl-CoA carboxylase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ChREBP activates metabolic gene expression
Biotin transport and metabolism
Import of palmitoyl-CoA into the mitochondrial matrix
Fatty acyl-CoA biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016047 HLCS / holocarboxylase synthetase / P50747* / Q920N2* / holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)*  / reaction
 ENSGALG00000005439 ACACA / acetyl-CoA carboxylase / Q5SWU9* / Q13085* / acetyl-CoA carboxylase alpha* / acetyl-Coenzyme A carboxylase alpha*  / -






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr