ENSGALG00000016047


Gallus gallus

Features
Gene ID: ENSGALG00000016047
  
Biological name :HLCS
  
Synonyms : HLCS / holocarboxylase synthetase
  
Possible biological names infered from orthology : holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) / P50747 / Q920N2
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 106864786
Gene end: 106977050
  
Corresponding Affymetrix probe sets: Gga.13968.1.S1_s_at (Chicken Array)   GgaAffx.24836.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000029718
NCBI entrez gene - 418516     See in Manteia.
RefSeq - XM_015301496
RefSeq - XM_416725
swissprot - E1C4U9
Ensembl - ENSGALG00000016047
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hlcsENSDARG00000039934Danio rerio
 HLCSENSG00000159267Homo sapiens
 HlcsENSMUSG00000040820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003142  Biotin protein ligase, C-terminal
 IPR004143  Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain
 IPR004408  Biotin--acetyl-CoA-carboxylase ligase
 IPR019197  Biotin-protein ligase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009305 protein biotinylation IEA
 biological_processGO:0016570 histone modification IEA
 biological_processGO:0070781 response to biotin IEA
 biological_processGO:0071110 histone biotinylation IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005652 nuclear lamina IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 molecular_functionGO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity IEA
 molecular_functionGO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity IEA
 molecular_functionGO:0009374 biotin binding IEA
 molecular_functionGO:0018271 biotin-protein ligase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
Biotin transport and metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037238 PCCB / propionyl-CoA carboxylase beta subunit / P05166* / Q99MN9* / Propionyl-CoA carboxylase beta chain, mitochondrial *  / reaction
 ENSGALG00000005439 ACACA / acetyl-CoA carboxylase / Q5SWU9* / Q13085* / acetyl-CoA carboxylase alpha* / acetyl-Coenzyme A carboxylase alpha*  / reaction
 ENSGALG00000005043 ACACB* / E9Q4Z2* / O00763* / acetyl-CoA carboxylase beta* / acetyl-Coenzyme A carboxylase beta*  / reaction
 ENSGALG00000016872 PCCA / propionyl-CoA carboxylase alpha subunit / P05165* / Q91ZA3* / propionyl-Coenzyme A carboxylase, alpha polypeptide*  / reaction






 

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