ENSGALG00000016872


Gallus gallus

Features
Gene ID: ENSGALG00000016872
  
Biological name :PCCA
  
Synonyms : PCCA / propionyl-CoA carboxylase alpha subunit
  
Possible biological names infered from orthology : P05165 / propionyl-Coenzyme A carboxylase, alpha polypeptide / Q91ZA3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 143981590
Gene end: 144252563
  
Corresponding Affymetrix probe sets: GgaAffx.25098.1.S1_at (Chicken Array)   GgaAffx.25098.2.S1_at (Chicken Array)   GgaAffx.25098.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027209
Ensembl peptide - ENSGALP00000058893
Ensembl peptide - ENSGALP00000049532
NCBI entrez gene - 418774     See in Manteia.
RefSeq - XM_015274936
RefSeq - XM_416970
swissprot - A0A1L1RJG2
swissprot - A0A1D5P9X4
swissprot - F1P0M2
Ensembl - ENSGALG00000016872
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pccaENSDARG00000028982Danio rerio
 PCCAENSG00000175198Homo sapiens
 PccaENSMUSG00000041650Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCCC1 / methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial / Q96RQ3* / Q99MR8* / methylcrotonoyl-CoA carboxylase 1*ENSGALG0000000878539


Protein motifs (from Interpro)
Interpro ID Name
 IPR000089  Biotin/lipoyl attachment
 IPR001882  Biotin-binding site
 IPR005479  Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
 IPR005481  Biotin carboxylase-like, N-terminal domain
 IPR005482  Biotin carboxylase, C-terminal
 IPR011053  Single hybrid motif
 IPR011054  Rudiment single hybrid motif
 IPR011761  ATP-grasp fold
 IPR011764  Biotin carboxylation domain
 IPR013815  ATP-grasp fold, subdomain 1
 IPR016185  Pre-ATP-grasp domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004658 propionyl-CoA carboxylase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Biotin transport and metabolism
Propionyl-CoA catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016872 PCCA / propionyl-CoA carboxylase alpha subunit / P05165* / Q91ZA3* / propionyl-Coenzyme A carboxylase, alpha polypeptide*  / complex
 ENSGALG00000037238 PCCB / propionyl-CoA carboxylase beta subunit / P05166* / Q99MN9* / Propionyl-CoA carboxylase beta chain, mitochondrial *  / complex
 ENSGALG00000016047 HLCS / holocarboxylase synthetase / P50747* / Q920N2* / holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)*  / reaction






 

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