ENSGALG00000005509


Gallus gallus

Features
Gene ID: ENSGALG00000005509
  
Biological name :DPYD
  
Synonyms : dihydropyrimidine dehydrogenase / DPYD
  
Possible biological names infered from orthology : Dihydropyrimidine dehydrogenase [NADP(+)] / Q12882 / Q8CHR6
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 12568769
Gene end: 12891574
  
Corresponding Affymetrix probe sets: GgaAffx.3458.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008828
NCBI entrez gene - 429083     See in Manteia.
RefSeq - XM_004936570
RefSeq - XM_015290739
RefSeq - XM_426639
swissprot - E1C4J1
Ensembl - ENSGALG00000005509
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpyda.1ENSDARG00000102671Danio rerio
 dpyda.3ENSDARG00000086853Danio rerio
 dpydbENSDARG00000010267Danio rerio
 DPYDENSG00000188641Homo sapiens
 DpydENSMUSG00000033308Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005720  Dihydroorotate dehydrogenase domain
 IPR009051  Alpha-helical ferredoxin
 IPR013785  Aldolase-type TIM barrel
 IPR017896  4Fe-4S ferredoxin-type, iron-sulphur binding domain
 IPR017900  4Fe-4S ferredoxin, iron-sulphur binding, conserved site
 IPR023753  FAD/NAD(P)-binding domain
 IPR028261  Dihydroprymidine dehydrogenase domain II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006145 purine nucleobase catabolic process IEA
 biological_processGO:0006208 pyrimidine nucleobase catabolic process IEA
 biological_processGO:0006210 thymine catabolic process IEA
 biological_processGO:0006212 uracil catabolic process IEA
 biological_processGO:0006214 thymidine catabolic process IEA
 biological_processGO:0019483 beta-alanine biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA
 molecular_functionGO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Pyrimidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005509 DPYD / dihydropyrimidine dehydrogenase / Q12882* / Q8CHR6* / Dihydropyrimidine dehydrogenase [NADP(+)] *  / complex






 

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