ENSGALG00000006657


Gallus gallus

Features
Gene ID: ENSGALG00000006657
  
Biological name :MAPRE1
  
Synonyms : MAPRE1 / microtubule-associated protein RP/EB family member 1
  
Possible biological names infered from orthology : Q15691 / Q61166
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10465102
Gene end: 10472787
  
Corresponding Affymetrix probe sets: Gga.5032.1.S1_s_at (Chicken Array)   GgaAffx.11910.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010754
Ensembl peptide - ENSGALP00000060923
Ensembl peptide - ENSGALP00000058765
NCBI entrez gene - 419288     See in Manteia.
RefSeq - NM_001030860
RefSeq - XM_015296403
RefSeq Peptide - NP_001026031
swissprot - A0A1L1RQ50
swissprot - A0A1I7Q3Z7
Ensembl - ENSGALG00000006657
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapre1aENSDARG00000042927Danio rerio
 mapre1bENSDARG00000002659Danio rerio
 MAPRE1ENSG00000101367Homo sapiens
 Mapre1ENSMUSG00000027479Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPRE3 / microtubule associated protein RP/EB family member 3 / Q6PER3* / Q9UPY8*ENSGALG0000003172667
MAPRE2 / microtubule-associated protein RP/EB family member 2 / Q15555* / Q8R001*ENSGALG0000001521560


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR004953  EB1, C-terminal
 IPR027328  Microtubule-associated protein RP/EB


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031115 negative regulation of microtubule polymerization IEA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:1903033 positive regulation of microtubule plus-end binding IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030981 cortical microtubule cytoskeleton IEA
 cellular_componentGO:0031253 cell projection membrane IEA
 cellular_componentGO:0035371 microtubule plus-end IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051010 microtubule plus-end binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006657 MAPRE1 / microtubule-associated protein RP/EB family member 1 / Q15691* / Q61166*  / complex






 

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contact: otassy@igbmc.fr