ENSMUSG00000027479


Mus musculus

Features
Gene ID: ENSMUSG00000027479
  
Biological name :Mapre1
  
Synonyms : Mapre1 / Microtubule-associated protein RP/EB family member 1 / Q61166
  
Possible biological names infered from orthology : Q15691
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 153741274
Gene end: 153773310
  
Corresponding Affymetrix probe sets: 10477353 (MoGene1.0st)   1422764_at (Mouse Genome 430 2.0 Array)   1422765_at (Mouse Genome 430 2.0 Array)   1428819_at (Mouse Genome 430 2.0 Array)   1428820_at (Mouse Genome 430 2.0 Array)   1450740_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028981
NCBI entrez gene - 13589     See in Manteia.
MGI - MGI:891995
RefSeq - NM_007896
RefSeq Peptide - NP_031922
swissprot - Q3U4H0
swissprot - Q61166
Ensembl - ENSMUSG00000027479
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapre1aENSDARG00000042927Danio rerio
 mapre1bENSDARG00000002659Danio rerio
 MAPRE1ENSGALG00000006657Gallus gallus
 MAPRE1ENSG00000101367Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mapre3 / Q6PER3 / Microtubule-associated protein RP/EB family member 3 / Q9UPY8*ENSMUSG0000002916666
Mapre2 / Q8R001 / Microtubule-associated protein RP/EB family member 2 / Q15555*ENSMUSG0000002427759


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR004953  EB1, C-terminal
 IPR027328  Microtubule-associated protein RP/EB
 IPR027739  EB1, Metazoa
 IPR036133  EB1, C-terminal domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031115 negative regulation of microtubule polymerization IEA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:1903033 positive regulation of microtubule plus-end binding IGI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0030981 cortical microtubule cytoskeleton ISO
 cellular_componentGO:0031253 cell projection membrane IDA
 cellular_componentGO:0035371 microtubule plus-end IDA
 cellular_componentGO:0042995 cell projection IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051010 microtubule plus-end binding ISO


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022385 Gtse1 / Q8R080 / G2 and S phase-expressed protein 1 / Q9NYZ3* / G2 and S-phase expressed 1*  / complex / reaction
 ENSMUSG00000027479 Mapre1 / Q61166 / Microtubule-associated protein RP/EB family member 1 / Q15691*  / complex






 

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