ENSGALG00000006707


Gallus gallus

Features
Gene ID: ENSGALG00000006707
  
Biological name :NOX1
  
Synonyms : NADPH oxidase 1 / NOX1
  
Possible biological names infered from orthology : Q8CIZ9 / Q9Y5S8
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 5186095
Gene end: 5190017
  
Corresponding Affymetrix probe sets: GgaAffx.22036.3.S1_s_at (Chicken Array)   GgaAffx.22036.4.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010835
NCBI entrez gene - 422257     See in Manteia.
RefSeq - XM_015278273
RefSeq - NM_001101830
RefSeq - XM_015278271
RefSeq - XM_015278272
RefSeq - XM_015278269
RefSeq - XM_015278270
RefSeq Peptide - NP_001095300
swissprot - F1NEJ0
Ensembl - ENSGALG00000006707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nox1ENSDARG00000087574Danio rerio
 NOX1ENSG00000007952Homo sapiens
 Nox1ENSMUSG00000031257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYBB / cytochrome b-245 beta chain / P04839* / Q61093* / Cytochrome b-245 heavy chain *ENSGALG0000001626155
NOX3 / NADPH oxidase 3 / Q672J9* / Q9HBY0*ENSGALG0000001365949
NOX4 / NADPH oxidase 4 / Q9JHI8* / Q9NPH5*ENSGALG0000001723534
DUOX1* / DUOX2* / Q9NRD8* / Q9NRD9* / dual oxidase 1* / dual oxidase 2*ENSGALG0000004151029
NOX5 / NADPH oxidase 5 / Q96PH1*ENSGALG0000000806328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000778  Cytochrome b245, heavy chain
 IPR013112  FAD-binding 8
 IPR013121  Ferric reductase, NAD binding domain
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel
 IPR029650  NADPH oxidase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0042554 superoxide anion generation IEA
 biological_processGO:0042743 hydrogen peroxide metabolic process IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045726 positive regulation of integrin biosynthetic process IEA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0051454 intracellular pH elevation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071455 cellular response to hyperoxia IEA
 biological_processGO:0072592 oxygen metabolic process IEA
 biological_processGO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1990451 cellular stress response to acidic pH IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043020 NADPH oxidase complex IEA
 cellular_componentGO:0071438 invadopodium membrane IEA
 molecular_functionGO:0016175 superoxide-generating NADPH oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate NADPH Oxidases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr