ENSGALG00000006818


Gallus gallus

Features
Gene ID: ENSGALG00000006818
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : KMT2A / lysine methyltransferase 2A / Mus musculus lysine (K)-specific methyltransferase 2A (Kmt2a), transcript variant 1, mRNA. / P55200 / Q03164
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 4346754
Gene end: 4388918
  
Corresponding Affymetrix probe sets: Gga.414.1.S1_at (Chicken Array)   Gga.4758.1.S1_at (Chicken Array)   GgaAffx.4240.1.S1_at (Chicken Array)   GgaAffx.4297.1.S1_at (Chicken Array)   GgaAffx.4309.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011008
Ensembl peptide - ENSGALP00000053163
NCBI entrez gene - 414897     See in Manteia.
RefSeq - XM_015298064
swissprot - A0A1D5PK13
swissprot - F1NET5
Ensembl - ENSGALG00000006818
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kmt2aENSDARG00000004537Danio rerio
 KMT2AENSG00000118058Homo sapiens
 Kmt2aENSMUSG00000002028Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KMT2D* / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *ENSGALG000000317028
SETD1B / histone-lysine N-methyltransferase SETD1B / Q8CFT2* / Q9UPS6* / SET domain containing 1B*ENSGALG000000043247
KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSGALG000000437382
KMT2D* / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *ENSGALG000000355012
KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSGALG000000326001


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001487  Bromodomain
 IPR001965  Zinc finger, PHD-type
 IPR002857  Zinc finger, CXXC-type
 IPR003616  Post-SET domain
 IPR003888  FY-rich, N-terminal
 IPR003889  FY-rich, C-terminal
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016569  Methyltransferase, trithorax
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0051568 histone H3-K4 methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0035097 histone methyltransferase complex IEA
 cellular_componentGO:0071339 MLL1 complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016022 RUNX1 / runt related transcription factor 1 / Q01196*  / complex / reaction






 

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