ENSGALG00000006829


Gallus gallus

Features
Gene ID: ENSGALG00000006829
  
Biological name :SMG1
  
Synonyms : SMG1 / SMG1, nonsense mediated mRNA decay associated PI3K related kinase
  
Possible biological names infered from orthology : Q8BKX6 / Q96Q15 / Serine/threonine-protein kinase SMG1
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 8372762
Gene end: 8430577
  
Corresponding Affymetrix probe sets: GgaAffx.11323.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011024
Ensembl peptide - ENSGALP00000051086
Ensembl peptide - ENSGALP00000044655
NCBI entrez gene - 416605     See in Manteia.
RefSeq - XM_015294535
RefSeq - XM_414907
swissprot - E1BW33
swissprot - A0A1D5PE85
swissprot - A0A1D5NWB7
Ensembl - ENSGALG00000006829
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smg1ENSDARG00000054570Danio rerio
 SMG1ENSG00000157106Homo sapiens
 Smg1ENSMUSG00000030655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTOR / mechanistic target of rapamycin kinase / P42345* / Q9JLN9* / Serine/threonine-protein kinase mTOR *ENSGALG0000000333911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR003152  FATC domain
 IPR011009  Protein kinase-like domain superfamily
 IPR014009  PIK-related kinase
 IPR016024  Armadillo-type fold
 IPR018936  Phosphatidylinositol 3/4-kinase, conserved site
 IPR031559  Serine/threonine-protein kinase SMG1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0032204 regulation of telomere maintenance IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:2001020 regulation of response to DNA damage stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042162 telomeric DNA binding IEA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003220 UPF1 / UPF1, RNA helicase and ATPase / Q92900* / Q9EPU0* / UPF1 regulator of nonsense transcripts homolog (yeast)*  / complex






 

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