ENSDARG00000054570


Danio rerio

Features
Gene ID: ENSDARG00000054570
  
Biological name :smg1
  
Synonyms : smg1 / SMG1 phosphatidylinositol 3-kinase-related kinase
  
Possible biological names infered from orthology : Q8BKX6 / Q96Q15 / Serine/threonine-protein kinase SMG1 / SMG1, nonsense mediated mRNA decay associated PI3K related kinase
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 31118026
Gene end: 31158437
  
Corresponding Affymetrix probe sets: Dr.17460.1.A1_at (Zebrafish Array)   NM_001080044_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000071267
Ensembl peptide - ENSDARP00000071235
NCBI entrez gene - 569810     See in Manteia.
RefSeq - XM_009299454
RefSeq - NM_001080044
RefSeq - XM_009299453
RefSeq Peptide - NP_001073513
swissprot - F6NHQ0
swissprot - C5J7W8
swissprot - F1QLT4
ZFIN ID - ZDB-GENE-061013-767
Ensembl - ENSDARG00000054570
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMG1ENSGALG00000006829Gallus gallus
 SMG1ENSG00000157106Homo sapiens
 Smg1ENSMUSG00000030655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mtor / mechanistic target of rapamycin kinase / P42345* / Q9JLN9* / Serine/threonine-protein kinase mTOR *ENSDARG0000005319612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR003152  FATC domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR018936  Phosphatidylinositol 3/4-kinase, conserved site
 IPR031559  Serine/threonine-protein kinase SMG1
 IPR035175  Serine/threonine-protein kinase SMG1, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IBA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000061378 smg8 / SMG8 nonsense mediated mRNA decay factor / Q8ND04* / Q8VE18* / AC099850.2* / Protein SMG8 *  / complex
 ENSDARG00000076627 smg9 / smg9 nonsense mediated mRNA decay factor / Q9DB90* / Q9H0W8* / Protein SMG9 *  / complex






 

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