ENSGALG00000007367


Gallus gallus

Features
Gene ID: ENSGALG00000007367
  
Biological name :WFIKKN2
  
Synonyms : WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 / WFIKKN2
  
Possible biological names infered from orthology : Q7TQN3 / Q8TEU8
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 10189967
Gene end: 10193843
  
Corresponding Affymetrix probe sets: Gga.17704.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011904
NCBI entrez gene - 422097     See in Manteia.
RefSeq - XM_420100
swissprot - E1C6W9
Ensembl - ENSGALG00000007367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wfikkn2aENSDARG00000013460Danio rerio
 wfikkn2bENSDARG00000059139Danio rerio
 Q8TEU8ENSG00000173714Homo sapiens
 Q7TQN3ENSMUSG00000044177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WFIKKN1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q8R0S6* / Q96NZ8* / WAP, FS, Ig, KU, and NTR-containing protein 1*ENSGALG0000000004456
SPINT1 / serine peptidase inhibitor, Kunitz type 1 / O43278* / Q9R097* / Kunitz-type protease inhibitor 1 *ENSGALG0000000846916
AMBP / protein AMBP precursor / P02760* / Q07456* / alpha-1-microglobulin/bikunin precursor* / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin*ENSGALG0000003025511
TFPI / tissue factor pathway inhibitor / O54819* / P10646*ENSGALG0000000259410
TFPI2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSGALG000000095128


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR002350  Kazal domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR018933  Netrin module, non-TIMP type
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR033639  WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:1900116 extracellular negative regulation of signal transduction IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA
 molecular_functionGO:0048019 receptor antagonist activity IEA
 molecular_functionGO:0050431 transforming growth factor beta binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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