ENSGALG00000030255


Gallus gallus

Features
Gene ID: ENSGALG00000030255
  
Biological name :AMBP
  
Synonyms : AMBP / protein AMBP precursor
  
Possible biological names infered from orthology : alpha-1-microglobulin/bikunin precursor / P02760 / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin / Q07456
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 1125509
Gene end: 1130778
  
Corresponding Affymetrix probe sets: Gga.11647.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056401
NCBI entrez gene - 770795     See in Manteia.
RefSeq - NM_001277698
RefSeq Peptide - NP_001264627
swissprot - A0A1D5PU00
Ensembl - ENSGALG00000030255
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ambpENSDARG00000004296Danio rerio
 AMBPENSG00000106927Homo sapiens
 AmbpENSMUSG00000028356Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WFIKKN1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q8R0S6* / Q96NZ8* / WAP, FS, Ig, KU, and NTR-containing protein 1*ENSGALG0000000004420
WFIKKN2 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 / Q7TQN3* / Q8TEU8*ENSGALG0000000736719
SPINT1 / serine peptidase inhibitor, Kunitz type 1 / O43278* / Q9R097* / Kunitz-type protease inhibitor 1 *ENSGALG0000000846918
TFPI / tissue factor pathway inhibitor / O54819* / P10646*ENSGALG0000000259413
TFPI2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSGALG0000000951213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR002345  Lipocalin
 IPR002968  Alpha-1-microglobulin
 IPR012674  Calycin
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR029856  Protein AMBP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0019862 IgA binding IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Scavenging of heme from plasma


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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