ENSDARG00000004296


Danio rerio

Features
Gene ID: ENSDARG00000004296
  
Biological name :ambp
  
Synonyms : alpha-1-microglobulin/bikunin precursor / ambp
  
Possible biological names infered from orthology : P02760 / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin / Q07456
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 10801564
Gene end: 10824286
  
Corresponding Affymetrix probe sets: Dr.2426.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000011426
Ensembl peptide - ENSDARP00000145080
NCBI entrez gene - 394093     See in Manteia.
swissprot - A7E2Q2
ZFIN ID - ZDB-GENE-040426-1608
Ensembl - ENSDARG00000004296
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMBPENSGALG00000030255Gallus gallus
 AMBPENSG00000106927Homo sapiens
 AmbpENSMUSG00000028356Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spint1b / serine peptidase inhibitor, Kunitz type 1 b / O43278* / Q9R097* / SPINT1* / Kunitz-type protease inhibitor 1 * / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000001246720
wfikkn2a / info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a / Q8TEU8* / Q7TQN3* / WFIKKN2* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin dom...ENSDARG0000001346017
spint1a / serine peptidase inhibitor, Kunitz type 1 a / O43278* / SPINT1* / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000010233217
spint2 / serine peptidase inhibitor, Kunitz type, 2 / O43291* / Q9WU03* / AC011479.1* / Kunitz-type protease inhibitor 2 *ENSDARG0000006947616
wfikkn2b / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b / Q7TQN3* / Q8TEU8* / WFIKKN2* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain c...ENSDARG0000005913916
wfikkn1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q96NZ8*ENSDARG0000010136415
tfpi2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSDARG0000006135112
tfpia / tissue factor pathway inhibitor a / TFPI* / P10646* / O54819* / tissue factor pathway inhibitor*ENSDARG0000003471812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR002345  Lipocalin
 IPR002968  Alpha-1-microglobulin
 IPR012674  Calycin
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR029856  Protein AMBP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Scavenging of heme from plasma


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004296 ambp / alpha-1-microglobulin/bikunin precursor / P02760* / Q07456* / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin*  / complex / reaction






 

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