ENSDARG00000069476


Danio rerio

Features
Gene ID: ENSDARG00000069476
  
Biological name :spint2
  
Synonyms : serine peptidase inhibitor, Kunitz type, 2 / spint2
  
Possible biological names infered from orthology : AC011479.1 / Kunitz-type protease inhibitor 2 / O43291 / Q9WU03
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 20239141
Gene end: 20250516
  
Corresponding Affymetrix probe sets: Dr.8947.1.A1_at (Zebrafish Array)   Dr.8947.2.S1_at (Zebrafish Array)   NM_001077250_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000091926
Ensembl peptide - ENSDARP00000126920
NCBI entrez gene - 562009     See in Manteia.
RefSeq - NM_001077250
RefSeq Peptide - NP_001070718
swissprot - F1QEV7
swissprot - R4GEK7
ZFIN ID - ZDB-GENE-061013-323
Ensembl - ENSDARG00000069476
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC011479.1ENSG00000267748Homo sapiens
 O43291ENSG00000167642Homo sapiens
 Q9WU03ENSMUSG00000074227Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spint1a / serine peptidase inhibitor, Kunitz type 1 a / O43278* / SPINT1* / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000010233221
spint1b / serine peptidase inhibitor, Kunitz type 1 b / O43278* / Q9R097* / SPINT1* / Kunitz-type protease inhibitor 1 * / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000001246719
tfpia / tissue factor pathway inhibitor a / TFPI* / P10646* / O54819* / tissue factor pathway inhibitor*ENSDARG0000003471816
tfpi2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSDARG0000006135115
wfikkn1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q96NZ8*ENSDARG0000010136414
wfikkn2a / info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a / Q8TEU8* / Q7TQN3* / WFIKKN2* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin dom...ENSDARG0000001346013
ambp / alpha-1-microglobulin/bikunin precursor / P02760* / Q07456* / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin*ENSDARG0000000429613
wfikkn2b / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b / Q7TQN3* / Q8TEU8* / WFIKKN2* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain c...ENSDARG0000005913913


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR011106  Seven cysteines, N-terminal
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
MET Receptor Activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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