ENSDARG00000013460


Danio rerio

Features
Gene ID: ENSDARG00000013460
  
Biological name :wfikkn2a
  
Synonyms : info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a / wfikkn2a
  
Possible biological names infered from orthology : Q7TQN3 / Q8TEU8 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 / WFIKKN2
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 18097700
Gene end: 18104658
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000025648
swissprot - E7F0N3
ZFIN ID - ZDB-GENE-120914-1
Ensembl - ENSDARG00000013460
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WFIKKN2ENSGALG00000007367Gallus gallus
 Q8TEU8ENSG00000173714Homo sapiens
 Q7TQN3ENSMUSG00000044177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wfikkn2b / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b / Q7TQN3* / Q8TEU8* / WFIKKN2* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain c...ENSDARG0000005913965
wfikkn1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q96NZ8*ENSDARG0000010136440
spint1b / serine peptidase inhibitor, Kunitz type 1 b / O43278* / Q9R097* / SPINT1* / Kunitz-type protease inhibitor 1 * / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000001246715
spint1a / serine peptidase inhibitor, Kunitz type 1 a / O43278* / SPINT1* / serine peptidase inhibitor, Kunitz type 1*ENSDARG0000010233214
ambp / alpha-1-microglobulin/bikunin precursor / P02760* / Q07456* / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin*ENSDARG0000000429611
spint2 / serine peptidase inhibitor, Kunitz type, 2 / O43291* / Q9WU03* / AC011479.1* / Kunitz-type protease inhibitor 2 *ENSDARG0000006947610
tfpi2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSDARG000000613517
tfpia / tissue factor pathway inhibitor a / TFPI* / P10646* / O54819* / tissue factor pathway inhibitor*ENSDARG000000347187


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR002350  Kazal domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008197  WAP-type "four-disulfide core" domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR018933  Netrin module, non-TIMP type
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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