ENSGALG00000007494


Gallus gallus

Features
Gene ID: ENSGALG00000007494
  
Biological name :LARS
  
Synonyms : LARS / leucyl-tRNA synthetase
  
Possible biological names infered from orthology : Leucine--tRNA ligase, cytoplasmic / Q8BMJ2 / Q9P2J5
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 17887084
Gene end: 17910503
  
Corresponding Affymetrix probe sets: Gga.18531.1.S1_s_at (Chicken Array)   Gga.7312.1.S1_at (Chicken Array)   GgaAffx.22261.1.S1_s_at (Chicken Array)   GgaAffx.4666.1.S1_at (Chicken Array)   GgaAffx.4666.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012100
NCBI entrez gene - 416347     See in Manteia.
RefSeq - XM_004945042
RefSeq - XM_414663
swissprot - E1C2I9
Ensembl - ENSGALG00000007494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 larsaENSDARG00000090988Danio rerio
 larsbENSDARG00000019280Danio rerio
 LARSENSG00000133706Homo sapiens
 LarsENSMUSG00000024493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002300  Aminoacyl-tRNA synthetase, class Ia
 IPR004493  Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic
 IPR009008  Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR013155  Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006425 glutaminyl-tRNA aminoacylation IEA
 biological_processGO:0006429 leucyl-tRNA aminoacylation IBA
 biological_processGO:0006438 valyl-tRNA aminoacylation IBA
 biological_processGO:0006622 protein targeting to lysosome IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010507 negative regulation of autophagy IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071233 cellular response to leucine IEA
 biological_processGO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity IEA
 biological_processGO:1904263 positive regulation of TORC1 signaling IEA
 biological_processGO:1990253 cellular response to leucine starvation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002161 aminoacyl-tRNA editing activity IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004819 glutamine-tRNA ligase activity IEA
 molecular_functionGO:0004823 leucine-tRNA ligase activity IBA
 molecular_functionGO:0004832 valine-tRNA ligase activity IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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