ENSGALG00000007650


Gallus gallus

Features
Gene ID: ENSGALG00000007650
  
Biological name :SLC9A3R1
  
Synonyms : Na(+)/H(+) exchange regulatory cofactor NHE-RF1 / SLC9A3R1
  
Possible biological names infered from orthology : O14745 / P70441 / SLC9A3 regulator 1 / solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 10530985
Gene end: 10538278
  
Corresponding Affymetrix probe sets: Gga.1222.2.S1_s_at (Chicken Array)   GgaAffx.4778.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012367
NCBI entrez gene - 422108     See in Manteia.
RefSeq - NM_001006424
RefSeq Peptide - NP_001006424
swissprot - F1NK29
Ensembl - ENSGALG00000007650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc9a3r1aENSDARG00000000068Danio rerio
 O14745ENSG00000109062Homo sapiens
 P70441ENSMUSG00000020733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SLC9A3R2 / SLC9A3 regulator 2 / Q15599* / solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2*ENSGALG0000000560848
PDZK1 / PDZ domain containing 1 / Q5T2W1* / Na(+)/H(+) exchange regulatory cofactor NHE-RF3 *ENSGALG0000001549227
PDZD3 / PDZ domain containing 3 / Q86UT5*ENSGALG0000000677922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR015098  EBP50, C-terminal
 IPR017300  Na(+)/H(+) exchange regulatory cofactor NHERF
 IPR031199  Na(+)/H(+) exchange regulatory cofactor NHERF-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003096 renal sodium ion transport IEA
 biological_processGO:0007097 nuclear migration IEA
 biological_processGO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0010766 negative regulation of sodium ion transport IEA
 biological_processGO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0019933 cAMP-mediated signaling IEA
 biological_processGO:0022612 gland morphogenesis IEA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030643 cellular phosphate ion homeostasis IEA
 biological_processGO:0032416 negative regulation of sodium:proton antiporter activity IEA
 biological_processGO:0032782 bile acid secretion IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0034635 glutathione transport IEA
 biological_processGO:0044062 regulation of excretion IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IEA
 biological_processGO:0051683 establishment of Golgi localization IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0060088 auditory receptor cell stereocilium organization IEA
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway IEA
 biological_processGO:0070293 renal absorption IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097291 renal phosphate ion absorption IEA
 biological_processGO:2000146 negative regulation of cell motility IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031526 brush border membrane IEA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0032426 stereocilium tip IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071944 cell periphery IEA
 cellular_componentGO:0097225 sperm midpiece IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0017081 chloride channel regulator activity IEA
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0031698 beta-2 adrenergic receptor binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0050780 dopamine receptor binding IEA
 molecular_functionGO:0070851 growth factor receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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