ENSGALG00000007665


Gallus gallus

Features
Gene ID: ENSGALG00000007665
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : DNA polymerase epsilon, catalytic subunit / POLE / polymerase (DNA directed), epsilon / Q07864 / Q9WVF7
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 10059096
Gene end: 10072074
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000012408
Ensembl peptide - ENSGALP00000054722
NCBI entrez gene - 416997     See in Manteia.
RefSeq - XM_001233984
swissprot - A0A1D5PPC3
swissprot - E1C5P2
Ensembl - ENSGALG00000007665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 poleENSDARG00000058533Danio rerio
 POLEENSG00000177084Homo sapiens
 PoleENSMUSG00000007080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POLE* / Q07864* / Q9WVF7* / polymerase (DNA directed), epsilon* / DNA polymerase epsilon, catalytic subunit*ENSGALG000000393841


Protein motifs (from Interpro)
Interpro ID Name
 IPR006133  DNA-directed DNA polymerase, family B, exonuclease domain
 IPR006134  DNA-directed DNA polymerase, family B, multifunctional domain
 IPR006172  DNA-directed DNA polymerase, family B
 IPR012337  Ribonuclease H-like superfamily
 IPR029703  DNA polymerase epsilon catalytic subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006272 leading strand elongation IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006287 base-excision repair, gap-filling IBA
 biological_processGO:0006297 nucleotide-excision repair, DNA gap filling IBA
 biological_processGO:0045004 DNA replication proofreading IBA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0008622 epsilon DNA polymerase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA
 molecular_functionGO:0008310 single-stranded DNA 3"-5" exodeoxyribonuclease activity IBA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Dual Incision in GG-NER
Dual incision in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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