ENSGALG00000008320


Gallus gallus

Features
Gene ID: ENSGALG00000008320
  
Biological name :EDEM1
  
Synonyms : EDEM1 / ER degradation enhancing alpha-mannosidase like protein 1
  
Possible biological names infered from orthology : Q925U4 / Q92611
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 18660231
Gene end: 18670239
  
Corresponding Affymetrix probe sets: Gga.17487.1.S1_at (Chicken Array)   Gga.5466.1.S1_at (Chicken Array)   GgaAffx.12311.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013528
NCBI entrez gene - 416110     See in Manteia.
RefSeq - NM_001006143
RefSeq Peptide - NP_001006143
swissprot - Q5ZK76
Ensembl - ENSGALG00000008320
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edem1ENSDARG00000025094Danio rerio
 EDEM1ENSG00000134109Homo sapiens
 Edem1ENSMUSG00000030104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EDEM3 / ER degradation enhancing alpha-mannosidase like protein 3 / Q2HXL6* / Q9BZQ6*ENSGALG0000000480637
EDEM2 / ER degradation enhancing alpha-mannosidase like protein 2 / Q9BV94*ENSGALG0000000312833


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0036510 trimming of terminal mannose on C branch IEA
 biological_processGO:0097466 ubiquitin-dependent glycoprotein ERAD pathway IEA
 biological_processGO:1904154 positive regulation of retrograde protein transport, ER to cytosol IEA
 biological_processGO:1904382 mannose trimming involved in glycoprotein ERAD pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IMP
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0051787 misfolded protein binding IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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