ENSGALG00000003128


Gallus gallus

Features
Gene ID: ENSGALG00000003128
  
Biological name :EDEM2
  
Synonyms : EDEM2 / ER degradation enhancing alpha-mannosidase like protein 2
  
Possible biological names infered from orthology : Q9BV94
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 2675951
Gene end: 2684090
  
Corresponding Affymetrix probe sets: GgaAffx.12035.1.S1_at (Chicken Array)   GgaAffx.1966.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004936
Ensembl peptide - ENSGALP00000057226
Ensembl peptide - ENSGALP00000051702
NCBI entrez gene - 770034     See in Manteia.
RefSeq - XM_003642498
RefSeq - XM_004946976
swissprot - A0A1D5PW95
swissprot - A0A1D5PFY5
swissprot - F1NAE0
Ensembl - ENSGALG00000003128
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edem2ENSDARG00000028448Danio rerio
 EDEM2ENSG00000088298Homo sapiens
 Edem2ENSMUSG00000038312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EDEM3 / ER degradation enhancing alpha-mannosidase like protein 3 / Q2HXL6* / Q9BZQ6*ENSGALG0000000480637
EDEM1 / ER degradation enhancing alpha-mannosidase like protein 1 / Q925U4* / Q92611*ENSGALG0000000832036


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 biological_processGO:0036509 trimming of terminal mannose on B branch IEA
 biological_processGO:0097466 ubiquitin-dependent glycoprotein ERAD pathway IEA
 biological_processGO:1904154 positive regulation of retrograde protein transport, ER to cytosol IEA
 biological_processGO:1904382 mannose trimming involved in glycoprotein ERAD pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IMP
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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