ENSMUSG00000038312


Mus musculus

Features
Gene ID: ENSMUSG00000038312
  
Biological name :Edem2
  
Synonyms : Edem2 / ER degradation enhancing alpha-mannosidase like protein 2
  
Possible biological names infered from orthology : Q9BV94
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 155701677
Gene end: 155729475
  
Corresponding Affymetrix probe sets: 10488912 (MoGene1.0st)   1423695_at (Mouse Genome 430 2.0 Array)   1444335_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041202
NCBI entrez gene - 108687     See in Manteia.
MGI - MGI:1915540
RefSeq - NM_145537
RefSeq - XM_006498555
RefSeq Peptide - NP_663512
swissprot - Q8BJT9
Ensembl - ENSMUSG00000038312
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edem2ENSDARG00000028448Danio rerio
 EDEM2ENSGALG00000003128Gallus gallus
 EDEM2ENSG00000088298Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Edem1 / Q925U4 / ER degradation-enhancing alpha-mannosidase-like protein 1 / Q92611*ENSMUSG0000003010438
Edem3 / Q2HXL6 / ER degradation-enhancing alpha-mannosidase-like protein 3 / Q9BZQ6*ENSMUSG0000004301938


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47
 IPR036026  Seven-hairpin glycosidases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 biological_processGO:0036509 trimming of terminal mannose on B branch IEA
 biological_processGO:0097466 ubiquitin-dependent glycoprotein ERAD pathway IEA
 biological_processGO:1904154 positive regulation of retrograde protein transport, ER to cytosol IDA
 biological_processGO:1904382 mannose trimming involved in glycoprotein ERAD pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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