ENSMUSG00000043019


Mus musculus

Features
Gene ID: ENSMUSG00000043019
  
Biological name :Edem3
  
Synonyms : Edem3 / ER degradation-enhancing alpha-mannosidase-like protein 3 / Q2HXL6
  
Possible biological names infered from orthology : Q9BZQ6
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: G1
Gene start: 151755371
Gene end: 151822051
  
Corresponding Affymetrix probe sets: 10350646 (MoGene1.0st)   1459133_at (Mouse Genome 430 2.0 Array)   1460401_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140443
Ensembl peptide - ENSMUSP00000140775
Ensembl peptide - ENSMUSP00000058941
Ensembl peptide - ENSMUSP00000140234
NCBI entrez gene - 66967     See in Manteia.
MGI - MGI:1914217
RefSeq - XM_017322085
RefSeq - XM_006529797
RefSeq - XM_006529798
RefSeq - XM_011248060
RefSeq - XM_011248061
RefSeq - XM_011248062
RefSeq - XM_011248063
RefSeq - XM_017322083
RefSeq - NM_001039644
RefSeq - NM_001311165
RefSeq - NM_001311166
RefSeq - XM_006529795
RefSeq - XM_006529796
RefSeq Peptide - NP_001298095
RefSeq Peptide - NP_001034733
RefSeq Peptide - NP_001298094
swissprot - A0A087WQK5
swissprot - Q2HXL6
swissprot - A0A087WR24
swissprot - B7ZNP0
Ensembl - ENSMUSG00000043019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edem3ENSDARG00000074129Danio rerio
 EDEM3ENSGALG00000004806Gallus gallus
 EDEM3ENSG00000116406Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Edem1 / Q925U4 / ER degradation-enhancing alpha-mannosidase-like protein 1 / Q92611*ENSMUSG0000003010424
Edem2 / ER degradation enhancing alpha-mannosidase like protein 2 / Q9BV94*ENSMUSG0000003831223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47
 IPR003137  PA domain
 IPR036026  Seven-hairpin glycosidases
 IPR037322  EDEM3, PA domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0006516 glycoprotein catabolic process IDA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:1904382 mannose trimming involved in glycoprotein ERAD pathway IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr