ENSGALG00000008947


Gallus gallus

Features
Gene ID: ENSGALG00000008947
  
Biological name :PAK5
  
Synonyms : p21 (RAC1) activated kinase 5 / PAK5
  
Possible biological names infered from orthology : Pak7 / Q8C015 / Q9P286 / Serine/threonine-protein kinase PAK 5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 13895067
Gene end: 13938400
  
Corresponding Affymetrix probe sets: Gga.15200.1.S1_s_at (Chicken Array)   Gga.16834.1.S1_at (Chicken Array)   GgaAffx.22738.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014534
NCBI entrez gene - 416734     See in Manteia.
RefSeq - XM_015283499
RefSeq - NM_001199409
RefSeq - XM_015283497
RefSeq - XM_015283498
RefSeq - XM_015283493
RefSeq - XM_015283494
RefSeq - XM_015283495
RefSeq - XM_015283496
RefSeq Peptide - NP_001186338
swissprot - E1BWY7
Ensembl - ENSGALG00000008947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pak7ENSDARG00000030154Danio rerio
 PAK5ENSG00000101349Homo sapiens
 Pak7ENSMUSG00000039913Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PAK6* / Q9NQU5* / Q3ULB5* / BUB1B-PAK6* / BUB1B-PAK6 readthrough* / p21 (RAC1) activated kinase 6* / Serine/threonine-protein kinase PAK 6 *ENSGALG0000003460544
PAK4 / p21 (RAC1) activated kinase 4 / O96013* / Q8BTW9* / Serine/threonine-protein kinase PAK 4 *ENSGALG0000003132842
PAK3 / p21 (RAC1) activated kinase 3 / O75914* / Q61036* / Serine/threonine-protein kinase PAK 3 *ENSGALG0000000805828
PAK1 / p21 (RAC1) activated kinase 1 / Q13153* / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA.*ENSGALG0000000068128
PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*ENSGALG0000000642627
TAOK3 / serine/threonine-protein kinase TAO3 / Q8BYC6* / Q9H2K8* / TAO kinase 3*ENSGALG0000000739616
TAOK1 / TAO kinase 1 / Q5F2E8* / Q7L7X3*ENSGALG0000000408216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR028754  Serine/threonine-protein kinase PAK5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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