ENSGALG00000009369


Gallus gallus

Features
Gene ID: ENSGALG00000009369
  
Biological name :PRDX3
  
Synonyms : peroxiredoxin 3 / PRDX3
  
Possible biological names infered from orthology : P20108 / P30048 / Thioredoxin-dependent peroxide reductase, mitochondrial
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 30049291
Gene end: 30054581
  
Corresponding Affymetrix probe sets: Gga.4515.2.S1_at (Chicken Array)   Gga.4515.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000059895
Ensembl peptide - ENSGALP00000063642
Ensembl peptide - ENSGALP00000062972
Ensembl peptide - ENSGALP00000060859
Ensembl peptide - ENSGALP00000060053
Ensembl peptide - ENSGALP00000015246
Ensembl peptide - ENSGALP00000050265
Ensembl peptide - ENSGALP00000054063
Ensembl peptide - ENSGALP00000054508
Ensembl peptide - ENSGALP00000059295
NCBI entrez gene - 428986     See in Manteia.
RefSeq - XM_426543
swissprot - E1BR10
swissprot - A0A1L1RKK7
swissprot - A0A1D5PNR4
swissprot - A0A1D5PBY3
Ensembl - ENSGALG00000009369
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdx3ENSDARG00000032102Danio rerio
 PRDX3ENSG00000165672Homo sapiens
 Prdx3ENSMUSG00000024997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRDX4 / peroxiredoxin 4 / O08807* / Q13162*ENSGALG0000001635758
PRDX1 / P0CB50 / Peroxiredoxin-1 / P35700* / Q06830*ENSGALG0000001024354


Protein motifs (from Interpro)
Interpro ID Name
 IPR000866  Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR019479  Peroxiredoxin, C-terminal
 IPR024706  Peroxiredoxin, AhpC-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001893 maternal placenta development IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0018171 peptidyl-cysteine oxidation IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033673 negative regulation of kinase activity IEA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0042744 hydrogen peroxide catabolic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0008385 IkappaB kinase complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008379 thioredoxin peroxidase activity IEA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
 molecular_functionGO:0051920 peroxiredoxin activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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