ENSGALG00000010243


Gallus gallus

Features
Gene ID: ENSGALG00000010243
  
Biological name :PRDX1
  
Synonyms : P0CB50 / Peroxiredoxin-1 / PRDX1
  
Possible biological names infered from orthology : P35700 / Q06830
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 21219080
Gene end: 21225390
  
Corresponding Affymetrix probe sets: Gga.5204.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048502
Ensembl peptide - ENSGALP00000060290
Ensembl peptide - ENSGALP00000016629
NCBI entrez gene - 424598     See in Manteia.
RefSeq - NM_001271932
RefSeq Peptide - NP_001258861
swissprot - A0A1D5P719
swissprot - P0CB50
Ensembl - ENSGALG00000010243
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdx1ENSDARG00000058734Danio rerio
 PRDX1ENSG00000117450Homo sapiens
 Prdx1ENSMUSG00000028691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRDX4 / peroxiredoxin 4 / O08807* / Q13162*ENSGALG0000001635770
PRDX3 / peroxiredoxin 3 / P20108* / P30048* / Thioredoxin-dependent peroxide reductase, mitochondrial *ENSGALG0000000936960


Protein motifs (from Interpro)
Interpro ID Name
 IPR000866  Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR019479  Peroxiredoxin, C-terminal
 IPR024706  Peroxiredoxin, AhpC-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000302 response to reactive oxygen species IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0019430 removal of superoxide radicals IEA
 biological_processGO:0030101 natural killer cell activation IEA
 biological_processGO:0032872 regulation of stress-activated MAPK cascade IEA
 biological_processGO:0034101 erythrocyte homeostasis IEA
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IEA
 biological_processGO:0042744 hydrogen peroxide catabolic process IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008379 thioredoxin peroxidase activity IEA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051920 peroxiredoxin activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010243 PRDX1 / P0CB50 / Peroxiredoxin-1 / P35700* / Q06830*  / complex
 ENSGALG00000015704 TXN / P08629 / Thioredoxin / Txn1* / TXNDC2* / P10599* / P10639* / Q86VQ3* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 2 (spermatozoa)*  / reaction






 

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