ENSDARG00000058734


Danio rerio

Features
Gene ID: ENSDARG00000058734
  
Biological name :prdx1
  
Synonyms : peroxiredoxin 1 / prdx1
  
Possible biological names infered from orthology : P35700 / Q06830
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 6104378
Gene end: 6115688
  
Corresponding Affymetrix probe sets: Dr.10624.1.S1_at (Zebrafish Array)   Dr.10624.2.S1_at (Zebrafish Array)   Dr.10624.2.S1_a_at (Zebrafish Array)   NM_001013471_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000076104
Ensembl peptide - ENSDARP00000140332
Ensembl peptide - ENSDARP00000116465
NCBI entrez gene - 541344     See in Manteia.
RefSeq - NM_001013471
RefSeq Peptide - NP_001013489
swissprot - A2AWE1
swissprot - A0A0R4IYJ8
ZFIN ID - ZDB-GENE-050320-35
Ensembl - ENSDARG00000058734
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRDX1ENSGALG00000010243Gallus gallus
 PRDX1ENSG00000117450Homo sapiens
 Prdx1ENSMUSG00000028691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prdx2 / peroxiredoxin 2 / Gm5225* / P32119* / Q61171*ENSDARG0000002535080
prdx4 / peroxiredoxin 4 / O08807* / Q13162*ENSDARG0000006901368
prdx3 / peroxiredoxin 3 / P20108* / P30048* / Thioredoxin-dependent peroxide reductase, mitochondrial *ENSDARG0000003210261


Protein motifs (from Interpro)
Interpro ID Name
 IPR000866  Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR019479  Peroxiredoxin, C-terminal
 IPR024706  Peroxiredoxin, AhpC-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0051920 peroxiredoxin activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction
 ENSDARG00000058734 prdx1 / peroxiredoxin 1 / P35700* / Q06830*  / complex
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction
 ENSDARG00000020693 sesn1 / sestrin 1 / P58006* / Q9Y6P5*  / reaction / complex
 ENSDARG00000070012 sesn2 / sestrin 2 / P58004* / P58043*  / complex / reaction






 

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