ENSGALG00000009519


Gallus gallus

Features
Gene ID: ENSGALG00000009519
  
Biological name :ARG2
  
Synonyms : ARG2 / arginase-2, mitochondrial
  
Possible biological names infered from orthology : arginase 2 / O08691 / P78540
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 28877454
Gene end: 28894773
  
Corresponding Affymetrix probe sets: Gga.10939.1.A1_at (Chicken Array)   Gga.10939.1.S1_at (Chicken Array)   Gga.8554.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043704
Ensembl peptide - ENSGALP00000015485
NCBI entrez gene - 423272     See in Manteia.
RefSeq - NM_001199704
RefSeq Peptide - NP_001186633
swissprot - F1P5B4
swissprot - A0A1D5NTP7
Ensembl - ENSGALG00000009519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arg2ENSDARG00000039269Danio rerio
 ARG2ENSG00000081181Homo sapiens
 Arg2ENSMUSG00000021125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGMAT / agmatinase, mitochondrial precursor / Q9BSE5* / A2AS89* / agmatinase* / Agmatinase, mitochondrial *ENSGALG0000003187220


Protein motifs (from Interpro)
Interpro ID Name
 IPR006035  Ureohydrolase
 IPR014033  Arginase
 IPR020855  Ureohydrolase, manganese-binding site
 IPR023696  Ureohydrolase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000050 urea cycle IEA
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0002829 negative regulation of type 2 immune response IEA
 biological_processGO:0006525 arginine metabolic process IEA
 biological_processGO:0006941 striated muscle contraction IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0050706 regulation of interleukin-1 beta secretion IEA
 biological_processGO:0071641 negative regulation of macrophage inflammatory protein 1 alpha production IEA
 biological_processGO:0071644 negative regulation of chemokine (C-C motif) ligand 4 production IEA
 biological_processGO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production IEA
 biological_processGO:1900425 negative regulation of defense response to bacterium IEA
 biological_processGO:1903426 regulation of reactive oxygen species biosynthetic process IEA
 biological_processGO:1904468 negative regulation of tumor necrosis factor secretion IEA
 biological_processGO:1905077 negative regulation of interleukin-17 secretion IEA
 biological_processGO:1905403 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process IEA
 biological_processGO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation IEA
 biological_processGO:2000666 negative regulation of interleukin-13 secretion IEA
 biological_processGO:2000774 positive regulation of cellular senescence IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004053 arginase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Urea cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009519 ARG2 / arginase-2, mitochondrial / O08691* / P78540* / arginase 2*  / complex






 

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