ENSGALG00000009551


Gallus gallus

Features
Gene ID: ENSGALG00000009551
  
Biological name :DYNC1I2
  
Synonyms : cytoplasmic dynein 1 intermediate chain 2 / DYNC1I2
  
Possible biological names infered from orthology : dynein cytoplasmic 1 intermediate chain 2 / Mus musculus dynein cytoplasmic 1 intermediate chain 2 (Dync1i2), transcript variant 9, mRNA. / O88487 / Q13409
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 18047522
Gene end: 18071958
  
Corresponding Affymetrix probe sets: GgaAffx.21443.1.S1_at (Chicken Array)   GgaAffx.6002.1.S1_s_at (Chicken Array)   GgaAffx.6002.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015531
Ensembl peptide - ENSGALP00000063689
Ensembl peptide - ENSGALP00000055685
Ensembl peptide - ENSGALP00000051944
NCBI entrez gene - 424151     See in Manteia.
RefSeq - NM_001006519
RefSeq Peptide - NP_001006519
swissprot - A0A1L1RXW6
swissprot - A0A1D5PS06
swissprot - A0A1D5PGM1
swissprot - F1P3C8
Ensembl - ENSGALG00000009551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dync1i2aENSDARG00000078386Danio rerio
 dync1i2bENSDARG00000103195Danio rerio
 Q13409ENSG00000077380Homo sapiens
 O88487ENSMUSG00000027012Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYNC1I1 / dynein cytoplasmic 1 intermediate chain 1 / O14576* / O88485* / Cytoplasmic dynein 1 intermediate chain 1 *ENSGALG0000000972277
WDR78 / WD repeat domain 78 / E9PYY5* / Q5VTH9*ENSGALG0000004579221
WDR34 / WD repeat domain 34 / Q96EX3*ENSGALG0000000470215
DNAI2 / dynein axonemal intermediate chain 2 / A2AC93* / Dnaic2* / Q9GZS0* / Dynein intermediate chain 2, axonemal *ENSGALG0000000449515
DNAI1 / dynein axonemal intermediate chain 1 / Q9UI46* / Dnaic1* / Q8C0M8* / Dynein intermediate chain 1, axonemal *ENSGALG0000000583114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR025956  Cytoplasmic dynein 1 intermediate chain 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0010970 transport along microtubule IBA
 biological_processGO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005868 cytoplasmic dynein complex IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0031982 vesicle IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045504 dynein heavy chain binding IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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