ENSDARG00000078386


Danio rerio

Features
Gene ID: ENSDARG00000078386
  
Biological name :dync1i2a
  
Synonyms : dync1i2a / dynein, cytoplasmic 1, intermediate chain 2a
  
Possible biological names infered from orthology : DYNC1I2 / dynein cytoplasmic 1 intermediate chain 2 / Mus musculus dynein cytoplasmic 1 intermediate chain 2 (Dync1i2), transcript variant 9, mRNA. / O88487 / Q13409
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 3170101
Gene end: 3234814
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000009095
Ensembl peptide - ENSDARP00000150754
Ensembl peptide - ENSDARP00000144159
Ensembl peptide - ENSDARP00000140613
Ensembl peptide - ENSDARP00000135779
Ensembl peptide - ENSDARP00000133144
NCBI entrez gene - 767729     See in Manteia.
RefSeq - NM_001076667
RefSeq Peptide - NP_001070135
swissprot - A0A0R4IU59
swissprot - A0A0R4IPR1
swissprot - A0A0R4IHQ1
swissprot - E7F6H7
swissprot - A0A286YAG4
ZFIN ID - ZDB-GENE-060929-1086
Ensembl - ENSDARG00000078386
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DYNC1I2ENSGALG00000009551Gallus gallus
 Q13409ENSG00000077380Homo sapiens
 O88487ENSMUSG00000027012Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dync1i2b / dynein, cytoplasmic 1, intermediate chain 2b / Q13409* / DYNC1I2* / dynein cytoplasmic 1 intermediate chain 2*ENSDARG0000010319584
dync1i1 / dynein, cytoplasmic 1, intermediate chain 1 / O14576* / O88485* / Cytoplasmic dynein 1 intermediate chain 1 *ENSDARG0000006094868
wdr78 / WD repeat domain 78 / E9PYY5* / Q5VTH9*ENSDARG0000004440020
dnai1.2 / dynein, axonemal, intermediate chain 1, paralog 2 / DNAI1* / Dnaic1* / Q8C0M8* / Q9UI46* / dynein axonemal intermediate chain 1* / Dynein intermediate chain 1, axonemal *ENSDARG0000003878819
dnai1.1 / dynein, axonemal, intermediate chain 1, paralog 1 / DNAI1* / Dnaic1* / Q8C0M8* / Q9UI46* / dynein axonemal intermediate chain 1* / Dynein intermediate chain 1, axonemal *ENSDARG0000010008115
dnai2b / dynein, axonemal, intermediate chain 2b / DNAI2* / Q9GZS0* / dynein axonemal intermediate chain 2*ENSDARG0000007408114
dnai2a / dynein, axonemal, intermediate chain 2aENSDARG0000010028514
wdr34 / WD repeat domain 34 / Q96EX3*ENSDARG0000005763514


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR025956  Cytoplasmic dynein 1 intermediate chain 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0010970 transport along microtubule IBA
 biological_processGO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
 cellular_componentGO:0005868 cytoplasmic dynein complex IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045504 dynein heavy chain binding IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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