ENSDARG00000060948


Danio rerio

Features
Gene ID: ENSDARG00000060948
  
Biological name :dync1i1
  
Synonyms : dync1i1 / dynein, cytoplasmic 1, intermediate chain 1
  
Possible biological names infered from orthology : Cytoplasmic dynein 1 intermediate chain 1 / O14576 / O88485
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 25316973
Gene end: 25337834
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000080844
NCBI entrez gene - 561525     See in Manteia.
RefSeq - XM_005158119
RefSeq - XM_009292244
RefSeq - NM_001079990
RefSeq Peptide - NP_001073459
swissprot - A1A5Y4
ZFIN ID - ZDB-GENE-061215-62
Ensembl - ENSDARG00000060948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DYNC1I1ENSGALG00000009722Gallus gallus
 O14576ENSG00000158560Homo sapiens
 O88485ENSMUSG00000029757Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dync1i2b / dynein, cytoplasmic 1, intermediate chain 2b / Q13409* / DYNC1I2* / dynein cytoplasmic 1 intermediate chain 2*ENSDARG0000010319570
dync1i2a / dynein, cytoplasmic 1, intermediate chain 2a / Q13409* / O88487* / DYNC1I2* / dynein cytoplasmic 1 intermediate chain 2* / Mus musculus dynein cytoplasmic 1 intermediate chain 2 ...ENSDARG0000007838668
wdr78 / WD repeat domain 78 / E9PYY5* / Q5VTH9*ENSDARG0000004440019
dnai1.2 / dynein, axonemal, intermediate chain 1, paralog 2 / DNAI1* / Dnaic1* / Q8C0M8* / Q9UI46* / dynein axonemal intermediate chain 1* / Dynein intermediate chain 1, axonemal *ENSDARG0000003878818
dnai2a / dynein, axonemal, intermediate chain 2aENSDARG0000010028515
dnai2b / dynein, axonemal, intermediate chain 2b / DNAI2* / Q9GZS0* / dynein axonemal intermediate chain 2*ENSDARG0000007408115
dnai1.1 / dynein, axonemal, intermediate chain 1, paralog 1 / DNAI1* / Dnaic1* / Q8C0M8* / Q9UI46* / dynein axonemal intermediate chain 1* / Dynein intermediate chain 1, axonemal *ENSDARG0000010008115
wdr34 / WD repeat domain 34 / Q96EX3*ENSDARG0000005763514


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR025956  Cytoplasmic dynein 1 intermediate chain 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0010970 transport along microtubule IBA
 biological_processGO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
 cellular_componentGO:0005868 cytoplasmic dynein complex IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045504 dynein heavy chain binding IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035924 dync1li2 / dynein, cytoplasmic 1, light intermediate chain 2 / O43237* / Q6PDL0* / Cytoplasmic dynein 1 light intermediate chain 2 *  / complex
 ENSDARG00000058454 dynll1 / dynein, light chain, LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSDARG00000056753 dctn1b / dynactin 1b / DCTN1* / O08788* / Q14203* / dynactin subunit 1* / Mus musculus dynactin 1 (Dctn1), transcript variant 4, mRNA.*  / complex
 ENSDARG00000100252 capzb / capping protein (actin filament) muscle Z-line, beta / P47756* / capping actin protein of muscle Z-line beta subunit*  / complex
 ENSDARG00000056090 capza1b / capping protein (actin filament) muscle Z-line, alpha 1b / P52907* / CAPZA1* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / complex
 ENSDARG00000060948 dync1i1 / dynein, cytoplasmic 1, intermediate chain 1 / O14576* / O88485* / Cytoplasmic dynein 1 intermediate chain 1 *  / complex
 ENSDARG00000019743 dctn1a / dynactin 1a / DCTN1* / Q14203* / dynactin subunit 1*  / complex
 ENSDARG00000041363 dctn3 / dynactin 3 (p22) / O75935* / Q9Z0Y1* / dynactin subunit 3*  / complex
 ENSDARG00000069790 dynll2a / dynein, light chain, LC8-type 2a / Q9D0M5* / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2* / Dynein light chain 2, cytoplasmic *  / complex
 ENSDARG00000098317 dync1li1 / dynein, cytoplasmic 1, light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / Cytoplasmic dynein 1 light intermediate chain 1 *  / complex






 

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