ENSGALG00000010410


Gallus gallus

Features
Gene ID: ENSGALG00000010410
  
Biological name :PFN2
  
Synonyms : PFN2 / profilin 2
  
Possible biological names infered from orthology : P35080 / Q9JJV2
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 23850758
Gene end: 23855806
  
Corresponding Affymetrix probe sets: GgaAffx.11987.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038130
NCBI entrez gene - 771904     See in Manteia.
RefSeq - NM_001079760
RefSeq - XM_015291695
RefSeq Peptide - NP_001073228
swissprot - Q5ZL50
Ensembl - ENSGALG00000010410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pfn2lENSDARG00000012682Danio rerio
 PFN2ENSG00000070087Homo sapiens
 Pfn2ENSMUSG00000027805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PFN3 / profilin 3 / P60673* / Q9DAD6*ENSGALG0000000945743


Protein motifs (from Interpro)
Interpro ID Name
 IPR005454  Profilin1/2/3, vertebrate
 IPR005455  Profilin
 IPR027310  Profilin conserved site
 IPR029891  Profilin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010633 negative regulation of epithelial cell migration IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0030837 negative regulation of actin filament polymerization IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0032233 positive regulation of actin filament bundle assembly IEA
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:1900028 negative regulation of ruffle assembly IEA
 biological_processGO:2000300 regulation of synaptic vesicle exocytosis IEA
 cellular_componentGO:0043195 terminal bouton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0016887 ATPase activity IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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