ENSGALG00000010620


Gallus gallus

Features
Gene ID: ENSGALG00000010620
  
Biological name :SPAST
  
Synonyms : Q5ZK92 / SPAST / Spastin
  
Possible biological names infered from orthology : Q9QYY8 / Q9UBP0
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 33711252
Gene end: 33743238
  
Corresponding Affymetrix probe sets: Gga.14001.1.A1_at (Chicken Array)   Gga.14001.1.S1_at (Chicken Array)   GgaAffx.12295.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017259
Ensembl peptide - ENSGALP00000062681
Ensembl peptide - ENSGALP00000060872
Ensembl peptide - ENSGALP00000060598
Ensembl peptide - ENSGALP00000045589
NCBI entrez gene - 421481     See in Manteia.
RefSeq - XM_015283728
RefSeq - XM_015283731
RefSeq - XM_015283730
RefSeq - XM_015283729
RefSeq - NM_001031061
RefSeq Peptide - NP_001026232
swissprot - Q5ZK92
swissprot - A0A1L1RV27
swissprot - A0A1D5NYX8
swissprot - A0A1L1RP85
swissprot - A0A1L1RPZ6
Ensembl - ENSGALG00000010620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spastENSDARG00000024933Danio rerio
 SPASTENSG00000021574Homo sapiens
 SpastENSMUSG00000024068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FIGN / fidgetin, microtubule severing factor / Q5HY92* / Q9ERZ6* / Fidgetin *ENSGALG0000001106925
FIGNL2 / fidgetin like 2 / A6NMB9*ENSGALG0000003333921
IQCA1 / IQ motif containing with AAA domain 1 / Iqca* / Q86XH1* / Q9CUL5* / IQ and AAA domain-containing protein 1 *ENSGALG0000000398015
FIGNL1* / Q6PIW4* / Q8BPY9* / fidgetin like 1* / Fidgetin-like protein 1 *ENSGALG000000263637


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR007330  MIT
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR017179  Spastin
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008089 anterograde axonal transport IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0019896 axonal transport of mitochondrion IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031468 nuclear envelope reassembly IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0032506 cytokinetic process IEA
 biological_processGO:0034214 protein hexamerization IEA
 biological_processGO:0051013 microtubule severing IEA
 biological_processGO:0051228 mitotic spindle disassembly IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090148 membrane fission IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008568 microtubule-severing ATPase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0043014 alpha-tubulin binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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