ENSGALG00000010769


Gallus gallus

Features
Gene ID: ENSGALG00000010769
  
Biological name :HPGD
  
Synonyms : 15-hydroxyprostaglandin dehydrogenase / HPGD
  
Possible biological names infered from orthology : 15-hydroxyprostaglandin dehydrogenase [NAD(+)] / P15428 / Q8VCC1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 44051784
Gene end: 44077636
  
Corresponding Affymetrix probe sets: Gga.9639.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000031565
NCBI entrez gene - 422567     See in Manteia.
RefSeq - NM_001277784
RefSeq - XM_015276239
RefSeq Peptide - NP_001264713
swissprot - E1C688
Ensembl - ENSGALG00000010769
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hpgdENSDARG00000012016Danio rerio
 HPGDENSG00000164120Homo sapiens
 HpgdENSMUSG00000031613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BDH2 / 3-hydroxybutyrate dehydrogenase 2 / Q8JZV9* / Q9BUT1* / 3-hydroxybutyrate dehydrogenase type 2 *ENSGALG0000001233826
ENSGALG0000000772725
CBR4 / carbonyl reductase 4 / Q8N4T8* / Q91VT4* / Carbonyl reductase family member 4 *ENSGALG0000000971424
DCXR / Q8JIS3 / D-erythrulose reductase / Cbr2* / Q91X52* / P08074* / Q7Z4W1* / L-xylulose reductase * / Carbonyl reductase [NADPH] 2 * / dicarbonyl and L-xylulose reductase*ENSGALG0000000284921


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain
 IPR020904  Short-chain dehydrogenase/reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006693 prostaglandin metabolic process IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007567 parturition IEA
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0097070 ductus arteriosus closure IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity IEA
 molecular_functionGO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0051287 NAD binding IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of Lipoxins (LX)
Biosynthesis of D-series resolvins
Biosynthesis of E-series 18(S)-resolvins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010769 HPGD / 15-hydroxyprostaglandin dehydrogenase / P15428* / Q8VCC1* / 15-hydroxyprostaglandin dehydrogenase [NAD(+)] *  / complex






 

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