ENSGALG00000010870


Gallus gallus

Features
Gene ID: ENSGALG00000010870
  
Biological name :JUN
  
Synonyms : JUN / transcription factor AP-1
  
Possible biological names infered from orthology : jun proto-oncogene / Jun proto-oncogene, AP-1 transcription factor subunit / P05412 / P05627
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 26451075
Gene end: 26452782
  
Corresponding Affymetrix probe sets: Gga.1473.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037247
NCBI entrez gene - 424673     See in Manteia.
RefSeq - NM_001031289
RefSeq Peptide - NP_001026460
swissprot - F1NCN0
Ensembl - ENSGALG00000010870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 junENSDARG00000043531Danio rerio
 JUNENSG00000177606Homo sapiens
 JunENSMUSG00000052684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JUND / JunD proto-oncogene, AP-1 transcription factor subunit / P15066* / P17535* / Transcription factor jun-D *ENSGALG0000004364152
JUNB* / P09450* / P17275* / Transcription factor jun-B * / JunB proto-oncogene, AP-1 transcription factor subunit*ENSGALG0000004193023


Protein motifs (from Interpro)
Interpro ID Name
 IPR002112  Transcription factor Jun
 IPR004827  Basic-leucine zipper domain
 IPR005643  Jun-like transcription factor
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR015558  Transcription Factor c-Jun/v-Jun


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001774 microglial cell activation IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007265 Ras protein signal transduction IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0030224 monocyte differentiation IEA
 biological_processGO:0031103 axon regeneration IEA
 biological_processGO:0031953 negative regulation of protein autophosphorylation IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0035026 leading edge cell differentiation IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0043922 negative regulation by host of viral transcription IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0061029 eyelid development in camera-type eye IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071276 cellular response to cadmium ion IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 biological_processGO:2000144 positive regulation of DNA-templated transcription, initiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005719 nuclear euchromatin IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 cellular_componentGO:0035976 transcription factor AP-1 complex IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035497 cAMP response element binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070412 R-SMAD binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
Activation of the AP-1 family of transcription factors
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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