ENSGALG00000011099


Gallus gallus

Features
Gene ID: ENSGALG00000011099
  
Biological name :FAP
  
Synonyms : FAP / prolyl endopeptidase FAP
  
Possible biological names infered from orthology : fibroblast activation protein alpha / P97321 / Prolyl endopeptidase FAP Antiplasmin-cleaving enzyme FAP, soluble form / Q12884
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 21188928
Gene end: 21227006
  
Corresponding Affymetrix probe sets: Gga.10039.1.S1_at (Chicken Array)   Gga.10098.1.S1_s_at (Chicken Array)   GgaAffx.23453.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018061
NCBI entrez gene - 424186     See in Manteia.
RefSeq - NM_001193639
RefSeq Peptide - NP_001180568
swissprot - F1NDP3
Ensembl - ENSGALG00000011099
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpp4ENSDARG00000079420Danio rerio
 fapENSDARG00000078468Danio rerio
 FAPENSG00000078098Homo sapiens
 FapENSMUSG00000000392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DPP4 / dipeptidyl peptidase 4 / P27487* / P28843* / Dipeptidyl peptidase 4 Dipeptidyl peptidase 4 membrane form Dipeptidyl peptidase 4 soluble form*ENSGALG0000004245256
DPP10 / dipeptidyl peptidase like 10 / Q8N608*ENSGALG0000001215633
DPP6 / dipeptidyl peptidase like 6 / P42658* / Q9Z218* / Dipeptidyl aminopeptidase-like protein 6 *ENSGALG0000004179130
DPP8 / dipeptidyl peptidase 8 / Q6V1X1* / Q80YA7*ENSGALG0000000743723
DPP9 / dipeptidyl peptidase 9 / Q86TI2* / Q8BVG4*ENSGALG0000000420021


Protein motifs (from Interpro)
Interpro ID Name
 IPR001375  Peptidase S9, prolyl oligopeptidase, catalytic domain
 IPR002469  Dipeptidylpeptidase IV, N-terminal domain
 IPR002471  Peptidase S9, serine active site
 IPR029058  Alpha/Beta hydrolase fold
 IPR031245  Dipeptidyl peptidase FAP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010710 regulation of collagen catabolic process IEA
 biological_processGO:0010716 negative regulation of extracellular matrix disassembly IEA
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 biological_processGO:0060244 negative regulation of cell proliferation involved in contact inhibition IEA
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 biological_processGO:0071850 mitotic cell cycle arrest IEA
 biological_processGO:0097325 melanocyte proliferation IEA
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IEA
 biological_processGO:1902362 melanocyte apoptotic process IEA
 biological_processGO:1903054 negative regulation of extracellular matrix organization IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0045178 basal part of cell IEA
 cellular_componentGO:0071438 invadopodium membrane IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0008239 dipeptidyl-peptidase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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