ENSGALG00000011219


Gallus gallus

Features
Gene ID: ENSGALG00000011219
  
Biological name :GCGR
  
Synonyms : GCGR / glucagon receptor
  
Possible biological names infered from orthology : P47871 / Q61606
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 9997747
Gene end: 10000701
  
Corresponding Affymetrix probe sets: GgaAffx.7122.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018272
NCBI entrez gene - 425670     See in Manteia.
RefSeq - NM_001101035
RefSeq - XM_015295408
RefSeq Peptide - NP_001094505
swissprot - A6N8N7
Ensembl - ENSGALG00000011219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcgraENSDARG00000104022Danio rerio
 gcgrbENSDARG00000036272Danio rerio
 GCGRENSG00000215644Homo sapiens
 GcgrENSMUSG00000025127Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000002889545
GLP1R / glucagon like peptide 1 receptor / O35659* / P43220*ENSGALG0000001007841
GLP2R / glucagon like peptide 2 receptor / O95838* / Q5IXF8*ENSGALG0000004180039
VIPR1 / vasoactive intestinal polypeptide receptor 1 precursor / P32241* / P97751* / vasoactive intestinal peptide receptor 1*ENSGALG0000000525933
VIPR2 / vasoactive intestinal peptide receptor 2 / P41587* / P41588*ENSGALG0000000657532
SCTR / secretin receptor / P47872* / Q5FWI2*ENSGALG0000001210631
ADCYAP1R1 / ADCYAP receptor type I / P41586* / P70205* / adenylate cyclase activating polypeptide 1 receptor 1*ENSGALG0000000522331
ENSGALG0000000524230
PTH1R / parathyroid hormone 1 receptor / P41593* / Q03431* / Parathyroid hormone/parathyroid hormone-related peptide receptor *ENSGALG0000000547629
growth hormone releasing hormone receptor precursor ENSGALG0000000027428
GHRHR / growth hormone releasing hormone receptor / P32082* / Q02643*ENSGALG0000000521227
ENSGALG0000001979727


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR003290  GPCR, family 2, glucagon-like peptide-1/glucagon receptor
 IPR003291  GPCR, family 2, glucagon receptor
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0070873 regulation of glycogen metabolic process IEA
 biological_processGO:0071377 cellular response to glucagon stimulus IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004967 glucagon receptor activity IEA


Pathways (from Reactome)
Pathway description
Glucagon signaling in metabolic regulation
G alpha (q) signalling events
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011104 GCG / P68259 / Glucagon Glicentin-related polypeptide Glucagon Glucagon-like peptide 1 Glucagon-like peptide 1(7-37) Glucagon-like peptide 1(7-36) Glucagon-like peptide 2 / P01275* / P55095...  / reaction / complex






 

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