ENSGALG00000011668


Gallus gallus

Features
Gene ID: ENSGALG00000011668
  
Biological name :IL8L1
  
Synonyms : IL8L1
  
Possible biological names infered from orthology : CXCL8 / C-X-C motif chemokine ligand 8 / P10145
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 51270481
Gene end: 51273558
  
Corresponding Affymetrix probe sets: Gga.512.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019049
NCBI entrez gene - 395872     See in Manteia.
RefSeq - NM_205018
RefSeq Peptide - NP_990349
swissprot - O73912
Ensembl - ENSGALG00000011668
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cxcl8aENSDARG00000104795Danio rerio
 CXCL8ENSG00000169429Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL8 / P08317 / Interleukin-8 / CXCL8* / P10145* / C-X-C motif chemokine ligand 8*ENSGALG0000002609866
PPBP* / CXCL5* / CXCL6* / CXCL1* / CXCL3* / CXCL2* / Q9WVL7* / Cxcl15* / P02775* / P09341* / P19875* / P19876* / P42830* / P80162* / C-X-C motif chemokine 15 * / pro-platelet basic protein*...ENSGALG0000004616036


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042119 neutrophil activation IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005153 interleukin-8 receptor binding IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0045236 CXCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036627 CXCR1 / CXCR2* / Q810W6* / P25024* / P25025* / P35343* / C-X-C chemokine receptor type 1 * / C-X-C motif chemokine receptor 2* / C-X-C motif chemokine receptor 1* / C-X-C chemokine receptor type 2 *  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr