Manteia

ENSGALG00000036627

Gallus gallus

Features

Gene ID:	ENSGALG00000036627

Biological name :	CXCR1

Synonyms :	CXCR1

Possible biological names infered from orthology :	C-X-C chemokine receptor type 1 / C-X-C chemokine receptor type 2 / C-X-C motif chemokine receptor 1 / C-X-C motif chemokine receptor 2 / CXCR2 / P25024 / P25025 / P35343 / Q810W6

Species:	Gallus gallus

Chr. number:	7
Strand:	1
Band:
Gene start:	22714676
Gene end:	22716777

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSGALP00000054150 NCBI entrez gene - 430652 See in Manteia. RefSeq - NM_001282432 RefSeq - XM_015289858 RefSeq Peptide - NP_001269361 swissprot - Q334G8 Ensembl - ENSGALG00000036627

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
cxcr2	ENSDARG00000054975	Danio rerio
CXCR1	ENSG00000163464	Homo sapiens
CXCR2	ENSG00000180871	Homo sapiens
Cxcr1	ENSMUSG00000048480	Mus musculus
Cxcr2	ENSMUSG00000026180	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
CXCR5 / C-X-C motif chemokine receptor 5 / P32302* / Q04683* / C-X-C chemokine receptor type 5 *	ENSGALG00000007675	34
CCR4 / C-C motif chemokine receptor 4 / P51679* / P51680* / C-C chemokine receptor type 4 *	ENSGALG00000039146	34
CCR7 / C-C motif chemokine receptor 7 / P32248* / P47774* / C-C chemokine receptor type 7 *	ENSGALG00000035733	33
CCR9 / C-C chemokine receptor type 9 / P51686* / Q9WUT7* / C-C motif chemokine receptor 9*	ENSGALG00000011808	32
CX3CR1 / C-X3-C motif chemokine receptor 1 / P49238* / Q9Z0D9* / CX3C chemokine receptor 1 *	ENSGALG00000038000	32
CXCR4 / C-X-C motif chemokine receptor 4 / P61073* / Mus musculus chemokine (C-X-C motif) receptor 4 (Cxcr4), transcript variant 2, mRNA.*	ENSGALG00000012357	32
CCR6 / C-C chemokine receptor type 6 / O54689* / P51684* / C-C motif chemokine receptor 6* / Mus musculus chemokine (C-C motif) receptor 6 (Ccr6), transcript variant 7, mRNA.*	ENSGALG00000011418	31
ACKR4 / atypical chemokine receptor 4 / Q924I3* / Q9NPB9*	ENSGALG00000041491	30
CCR10 / C-C motif chemokine receptor 10 / P46092* / Q9JL21* / C-C chemokine receptor type 10 *	ENSGALG00000028519	30
CCR8 / C-C motif chemokine receptor 8 / P51685* / P56484* / C-C chemokine receptor type 8 *	ENSGALG00000038069	29
CCR5 / CCR1* / CCR3* / CCR2* / P51681* / P41597* / P51675* / P51676* / P51677* / P51678* / P51682* / P51683* / Ccr1l1* / P32246* / C-C motif chemokine receptor 3* / C-C chemokine receptor t...	ENSGALG00000037077	29
CCR2 / C-C chemokine receptor type 2 / CCR1* / CCR5* / CCR3* / P51681* / P51683* / P51675* / P51676* / P51677* / P51678* / P51682* / Ccr1l1* / P32246* / P41597* / C-C motif chemokine recep...	ENSGALG00000011733	28
ACKR2 / atypical chemokine receptor 2 / O00590* / O08707*	ENSGALG00000005305	28
CCR8L / C-C chemokine receptor 8 like / CCR8* / P51685* / P56484* / C-C motif chemokine receptor 8* / C-C chemokine receptor type 8 *	ENSGALG00000011734	26
XCR1 / X-C motif chemokine receptor 1 / P46094* / chemokine (C motif) receptor 1*	ENSGALG00000011735	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR000174	CXC chemokine receptor 1/2
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006935	chemotaxis	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0070098	chemokine-mediated signaling pathway	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0016494	C-X-C chemokine receptor activity	IEA

Pathways (from Reactome)

Pathway description

Chemokine receptors bind chemokines

G alpha (i) signalling events

Neutrophil degranulation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000026098	IL8 / P08317 / Interleukin-8 / CXCL8* / P10145* / C-X-C motif chemokine ligand 8*	/ reaction / complex
ENSGALG00000011668	IL8L1 / CXCL8* / P10145* / C-X-C motif chemokine ligand 8*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr