ENSGALG00000012044


Gallus gallus

Features
Gene ID: ENSGALG00000012044
  
Biological name :ANK2
  
Synonyms : ANK2 / ankyrin 2
  
Possible biological names infered from orthology : Q01484 / Q8C8R3
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 57097275
Gene end: 57432432
  
Corresponding Affymetrix probe sets: Gga.13183.1.S1_at (Chicken Array)   Gga.15966.1.S1_at (Chicken Array)   Gga.756.1.S1_s_at (Chicken Array)   Gga.9555.1.S1_s_at (Chicken Array)   GgaAffx.23757.1.S1_at (Chicken Array)   GgaAffx.23757.2.S1_at (Chicken Array)   GgaAffx.23757.3.S1_s_at (Chicken Array)   GgaAffx.23757.5.S1_s_at (Chicken Array)   GgaAffx.23757.6.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046355
Ensembl peptide - ENSGALP00000048543
Ensembl peptide - ENSGALP00000019635
NCBI entrez gene - 422689     See in Manteia.
RefSeq - XM_015276352
RefSeq - XM_015276349
RefSeq - XM_015276350
RefSeq - XM_015276351
RefSeq - XM_015276343
RefSeq - XM_015276344
RefSeq - XM_015276345
RefSeq - XM_015276346
RefSeq - XM_015276347
RefSeq - XM_015276348
swissprot - A0A1D5P758
swissprot - F1NG08
swissprot - A0A1D5P124
Ensembl - ENSGALG00000012044
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ank2aENSDARG00000009026Danio rerio
 ank2bENSDARG00000043313Danio rerio
 ANK2ENSG00000145362Homo sapiens
 Ank2ENSMUSG00000032826Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANK3 / ankyrin 3 / G5E8K5* / Q12955*ENSGALG0000000313557
ANK1 / ankyrin 1 / P16157* / Q02357*ENSGALG0000000359442
TNKS2 / tankyrase-2 / Q3UES3* / Q9H2K2*ENSGALG0000001461415
TNKS / tankyrase-1 / O95271* / Q6PFX9* / tankyrase* / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase*ENSGALG0000004316415
ANKRD28 / ankyrin repeat domain 28 / O15084* / Q505D1* / Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A *ENSGALG0000001122614
ANKRD52 / serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C / Q8BTI7* / Q8NB46* / ankyrin repeat domain 52*ENSGALG0000003197314
Q5F478 / ANKRD44 / Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B / B2RXR6* / Q8N8A2* / ankyrin repeat domain 44*ENSGALG0000000799613
INVS / inversin / Q9Y283* / inversin isoform 2 *ENSGALG0000001344111
ENSGALG000000432458


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000906  ZU5 domain
 IPR002110  Ankyrin repeat
 IPR011029  Death-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0003283 atrial septum development IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IEA
 biological_processGO:0010882 regulation of cardiac muscle contraction by calcium ion signaling IEA
 biological_processGO:0033365 protein localization to organelle IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0051279 regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051924 regulation of calcium ion transport IEA
 biological_processGO:0055117 regulation of cardiac muscle contraction IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:0070972 protein localization to endoplasmic reticulum IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0086004 regulation of cardiac muscle cell contraction IEA
 biological_processGO:0086005 ventricular cardiac muscle cell action potential IEA
 biological_processGO:0086014 atrial cardiac muscle cell action potential IEA
 biological_processGO:0086070 SA node cell to atrial cardiac muscle cell communication IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098907 regulation of SA node cell action potential IEA
 biological_processGO:0098910 regulation of atrial cardiac muscle cell action potential IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0043034 costamere IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030507 spectrin binding IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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