ENSGALG00000012160


Gallus gallus

Features
Gene ID: ENSGALG00000012160
  
Biological name :KIF18A
  
Synonyms : KIF18A / kinesin family member 18A
  
Possible biological names infered from orthology : Kinesin-like protein KIF18A / Q8NI77 / Q91WD7
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 3836014
Gene end: 3878370
  
Corresponding Affymetrix probe sets: GgaAffx.7711.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019833
NCBI entrez gene - 421607     See in Manteia.
RefSeq - XM_015286168
RefSeq - NM_001199426
RefSeq - XM_015286166
RefSeq - XM_015286167
RefSeq Peptide - NP_001186355
swissprot - E1BUZ2
Ensembl - ENSGALG00000012160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif18aENSDARG00000008022Danio rerio
 KIF18AENSG00000121621Homo sapiens
 Kif18aENSMUSG00000027115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIF18B / Q5ZLK6 / Kinesin-like protein KIF18B / Q6PFD6* / Q86Y91* / kinesin family member 18B*ENSGALG0000003155334
KIF20B* / Q80WE4* / Q96Q89* / kinesin family member 20B* / Kinesin-like protein KIF20B *ENSGALG0000003841618
KIF24 / kinesin family member 24 / Q5T7B8* / Q6NWW5* / Kinesin-like protein KIF24 *ENSGALG0000000580618
KIF19 / kinesin family member 19 / Kif19a* / Q2TAC6* / Q99PT9* / Kinesin-like protein KIF19 *ENSGALG0000000450218
KIF23 / kinesin family member 23 / E9Q5G3* / Q02241* / Kinesin-like protein KIF23 *ENSGALG0000000809516
KIF2A / kinesin family member 2A / O00139* / P28740* / Kinesin-like protein KIF2A *ENSGALG0000001473716
KIF2C* / Q922S8* / Q99661* / kinesin family member 2C* / Kinesin-like protein KIF2C *ENSGALG0000001012016
KIF20A / kinesin family member 20A / O95235* / P97329* / Kinesin-like protein KIF20A *ENSGALG0000003503015
ENSGALG0000001540414
KIF20B* / Q80WE4* / Q96Q89* / kinesin family member 20B* / Kinesin-like protein KIF20B *ENSGALG0000003423213
KIF20B* / Q80WE4* / Q96Q89* / kinesin family member 20B* / Kinesin-like protein KIF20B *ENSGALG000000387994


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IBA
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0007019 microtubule depolymerization IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0007140 male meiotic nuclear division IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:0072520 seminiferous tubule development IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005828 kinetochore microtubule IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:1990023 mitotic spindle midzone IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0051010 microtubule plus-end binding IEA
 molecular_functionGO:0070463 tubulin-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
COPI-dependent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012160 KIF18A / kinesin family member 18A / Q8NI77* / Q91WD7* / Kinesin-like protein KIF18A *  / complex






 

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