ENSGALG00000012297


Gallus gallus

Features
Gene ID: ENSGALG00000012297
  
Biological name :GRM1
  
Synonyms : glutamate metabotropic receptor 1 / GRM1
  
Possible biological names infered from orthology : Metabotropic glutamate receptor 1 / P97772 / Q13255
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 46791540
Gene end: 46967947
  
Corresponding Affymetrix probe sets: GgaAffx.7793.1.S1_s_at (Chicken Array)   GgaAffx.7793.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049346
Ensembl peptide - ENSGALP00000020068
Ensembl peptide - ENSGALP00000044985
NCBI entrez gene - 421614     See in Manteia.
RefSeq - XM_419652
RefSeq - XM_015284286
RefSeq - XM_015284287
RefSeq - XM_015284288
RefSeq - XM_004935585
RefSeq - XM_015284285
swissprot - F1NBM2
swissprot - I3XHQ6
swissprot - A0A1D6UPQ5
Ensembl - ENSGALG00000012297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grm1aENSDARG00000026796Danio rerio
 grm1bENSDARG00000098320Danio rerio
 GRM1ENSG00000152822Homo sapiens
 Grm1ENSMUSG00000019828Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRM5 / metabotropic glutamate receptor 5 precursor / P41594* / Q3UVX5* / glutamate metabotropic receptor 5* / glutamate receptor, metabotropic 5*ENSGALG0000001723864
GRM8 / glutamate metabotropic receptor 8 / O00222* / P47743* / glutamate receptor, metabotropic 8*ENSGALG0000003940332
GRM3 / glutamate metabotropic receptor 3 / Q14832* / Q9QYS2* / Metabotropic glutamate receptor 3 *ENSGALG0000000657632
GRM4 / glutamate metabotropic receptor 4 / Q14833* / glutamate receptor, metabotropic 4*ENSGALG0000000284032
GRM7 / glutamate metabotropic receptor 7 / Q14831* / Q68ED2* / Metabotropic glutamate receptor 7 *ENSGALG0000003784131
GRM2 / glutamate metabotropic receptor 2 / Q14416* / Q14BI2* / Metabotropic glutamate receptor 2 *ENSGALG0000000383922
GPRC6A / G protein-coupled receptor class C group 6 member A / Q5T6X5* / Q8K4Z6* / G protein-coupled receptor, family C, group 6, member A*ENSGALG0000001492519
TAS1R1 / taste 1 receptor member 1 / Q7RTX1* / taste receptor, type 1, member 1*ENSGALG0000004603016
TAS1R3 / taste 1 receptor member 3 / Q7RTX0* / Q925D8* / Taste receptor type 1 member 3 *ENSGALG0000003231716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000162  GPCR, family 3, metabotropic glutamate receptor
 IPR000337  GPCR, family 3
 IPR001256  GPCR, family 3, metabotropic glutamate receptor 1
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR019588  Metabotropic glutamate receptor, Homer-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway IBA
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IEA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IBA
 biological_processGO:0071257 cellular response to electrical stimulus IEA
 biological_processGO:0099566 regulation of postsynaptic cytosolic calcium ion concentration IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0038037 G-protein coupled receptor dimeric complex IEA
 cellular_componentGO:0038038 G-protein coupled receptor homodimeric complex IEA
 cellular_componentGO:0042734 presynaptic membrane IBA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008066 glutamate receptor activity IEA
 molecular_functionGO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003074 HOMER3 / homer scaffolding protein 3 / Q99JP6* / Q9NSC5* / Homer protein homolog 3 *  / reaction / complex
 ENSGALG00000014813 HOMER1 / homer scaffolding protein 1 / Q86YM7* / Q9Z2Y3* / Homer protein homolog 1 *  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr