ENSGALG00000017238


Gallus gallus

Features
Gene ID: ENSGALG00000017238
  
Biological name :GRM5
  
Synonyms : GRM5 / metabotropic glutamate receptor 5 precursor
  
Possible biological names infered from orthology : glutamate metabotropic receptor 5 / glutamate receptor, metabotropic 5 / P41594 / Q3UVX5
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 188012289
Gene end: 188251626
  
Corresponding Affymetrix probe sets: Gga.73.1.S1_a_at (Chicken Array)   Gga.73.4.S1_at (Chicken Array)   Gga.73.4.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056964
Ensembl peptide - ENSGALP00000027813
Ensembl peptide - ENSGALP00000050787
Ensembl peptide - ENSGALP00000052133
NCBI entrez gene - 373933     See in Manteia.
RefSeq - XM_015279796
RefSeq - NM_204138
RefSeq - XM_015279789
RefSeq - XM_015279791
RefSeq - XM_015279794
RefSeq Peptide - NP_989469
swissprot - Q98UC6
swissprot - F1NWG3
swissprot - A0A1D5PDE2
swissprot - Q98UC5
Ensembl - ENSGALG00000017238
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grm5aENSDARG00000004445Danio rerio
 grm5bENSDARG00000102067Danio rerio
 GRM5ENSG00000168959Homo sapiens
 Grm5ENSMUSG00000049583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRM1 / glutamate metabotropic receptor 1 / P97772* / Q13255* / Metabotropic glutamate receptor 1 *ENSGALG0000001229759
GRM3 / glutamate metabotropic receptor 3 / Q14832* / Q9QYS2* / Metabotropic glutamate receptor 3 *ENSGALG0000000657631
GRM8 / glutamate metabotropic receptor 8 / O00222* / P47743* / glutamate receptor, metabotropic 8*ENSGALG0000003940330
GRM4 / glutamate metabotropic receptor 4 / Q14833* / glutamate receptor, metabotropic 4*ENSGALG0000000284030
GRM7 / glutamate metabotropic receptor 7 / Q14831* / Q68ED2* / Metabotropic glutamate receptor 7 *ENSGALG0000003784129
GRM2 / glutamate metabotropic receptor 2 / Q14416* / Q14BI2* / Metabotropic glutamate receptor 2 *ENSGALG0000000383920
GPRC6A / G protein-coupled receptor class C group 6 member A / Q5T6X5* / Q8K4Z6* / G protein-coupled receptor, family C, group 6, member A*ENSGALG0000001492517
TAS1R3 / taste 1 receptor member 3 / Q7RTX0* / Q925D8* / Taste receptor type 1 member 3 *ENSGALG0000003231716
TAS1R1 / taste 1 receptor member 1 / Q7RTX1* / taste receptor, type 1, member 1*ENSGALG0000004603015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000162  GPCR, family 3, metabotropic glutamate receptor
 IPR000202  GPCR, family 3, metabotropic glutamate receptor 5
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR019588  Metabotropic glutamate receptor, Homer-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006448 regulation of translational elongation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway IBA
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IEA
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0050890 cognition IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IBA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0090647 modulation of age-related behavioral decline IEA
 biological_processGO:0099566 regulation of postsynaptic cytosolic calcium ion concentration IEA
 biological_processGO:1902938 regulation of intracellular calcium activated chloride channel activity IEA
 biological_processGO:1904646 cellular response to amyloid-beta IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042734 presynaptic membrane IBA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008066 glutamate receptor activity IEA
 molecular_functionGO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential IEA
 molecular_functionGO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003074 HOMER3 / homer scaffolding protein 3 / Q99JP6* / Q9NSC5* / Homer protein homolog 3 *  / complex / reaction
 ENSGALG00000014813 HOMER1 / homer scaffolding protein 1 / Q86YM7* / Q9Z2Y3* / Homer protein homolog 1 *  / reaction / complex






 

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