ENSGALG00000012546


Gallus gallus

Features
Gene ID: ENSGALG00000012546
  
Biological name :MCM5
  
Synonyms : MCM5 / minichromosome maintenance complex component 5
  
Possible biological names infered from orthology : P33992
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 52144221
Gene end: 52165309
  
Corresponding Affymetrix probe sets: GgaAffx.12177.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020463
Ensembl peptide - ENSGALP00000061233
Ensembl peptide - ENSGALP00000044625
NCBI entrez gene - 418058     See in Manteia.
RefSeq - NM_001006243
RefSeq Peptide - NP_001006243
swissprot - A0A1L1RR09
swissprot - A0A1D5NW89
swissprot - Q5ZKL0
Ensembl - ENSGALG00000012546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcm5ENSDARG00000019507Danio rerio
 MCM5ENSG00000100297Homo sapiens
 Mcm5ENSMUSG00000005410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001208  MCM domain
 IPR008048  DNA replication licensing factor Mcm5
 IPR012340  Nucleic acid-binding, OB-fold
 IPR018525  Mini-chromosome maintenance, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027925  MCM N-terminal domain
 IPR031327  Mini-chromosome maintenance protein
 IPR033762  MCM OB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0042555 MCM complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003688 DNA replication origin binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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