ENSGALG00000012608


Gallus gallus

Features
Gene ID: ENSGALG00000012608
  
Biological name :DAPK1
  
Synonyms : DAPK1 / death-associated protein kinase 1 isoform 1
  
Possible biological names infered from orthology : death associated protein kinase 1 / P53355 / Q80YE7
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 41280442
Gene end: 41377445
  
Corresponding Affymetrix probe sets: Gga.16020.1.S1_at (Chicken Array)   Gga.9179.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020557
Ensembl peptide - ENSGALP00000052513
Ensembl peptide - ENSGALP00000043519
NCBI entrez gene - 431670     See in Manteia.
RefSeq - XM_015280320
RefSeq - NM_001031613
RefSeq - NM_001278031
RefSeq - XM_015280319
RefSeq Peptide - NP_001026784
RefSeq Peptide - NP_001264960
swissprot - E1C3M5
swissprot - A0A1D5PI81
swissprot - A0A1D5NT66
Ensembl - ENSGALG00000012608
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dapk1ENSDARG00000060093Danio rerio
 DAPK1ENSG00000196730Homo sapiens
 Dapk1ENSMUSG00000021559Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAPK3 / death associated protein kinase 3 / O43293* / O54784*ENSGALG0000003773319
DAPK2 / death associated protein kinase 2 / Q8VDF3* / Q9UIK4*ENSGALG0000000333616
SPEG* / Q15772* / Q62407* / SPEG complex locus*ENSGALG0000004319815
MYLK / Gallus gallus myosin light chain kinase (MYLK), transcript variant 1, mRNA. / Q15746* / myosin light chain kinase*ENSGALG0000001170812
ENSGALG0000002607011
MYLK3 / myosin light chain kinase 3 / Q32MK0* / Q3UIZ8*ENSGALG0000000433410
MYLK2 / myosin light chain kinase 2, skeletal/cardiac muscle / Q8VCR8* / Q9H1R3* / myosin light chain kinase 2*ENSGALG000000062739
STK17B / serine/threonine kinase 17b / O94768* / Q8BG48* / Serine/threonine-protein kinase 17B *ENSGALG000000079249
STK17A / serine/threonine-protein kinase 17A / Q9UEE5* / serine/threonine kinase 17a*ENSGALG000000311179
MYLK4 / myosin light chain kinase family member 4 / Q86YV6*ENSGALG000000128459
ENSGALG000000008249
SPEG* / Q15772* / Q62407* / SPEG complex locus*ENSGALG000000369730


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000719  Protein kinase domain
 IPR002110  Ankyrin repeat
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011029  Death-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR020676  Death-associated protein kinase 1
 IPR020683  Ankyrin repeat-containing domain
 IPR020859  Roc domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:0010508 positive regulation of autophagy IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:0071447 cellular response to hydroperoxide IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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