ENSGALG00000012894


Gallus gallus

Features
Gene ID: ENSGALG00000012894
  
Biological name :CHRM2
  
Synonyms : CHRM2 / Muscarinic acetylcholine receptor M2 / P30372
  
Possible biological names infered from orthology : cholinergic receptor muscarinic 2 / cholinergic receptor, muscarinic 2, cardiac / P08172 / Q9ERZ4
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 57864325
Gene end: 57865725
  
Corresponding Affymetrix probe sets: Gga.10240.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020999
NCBI entrez gene - 418126     See in Manteia.
RefSeq - XM_015285645
RefSeq - NM_001030765
RefSeq - XM_015285631
RefSeq - XM_015285640
RefSeq Peptide - NP_001025936
swissprot - P30372
Ensembl - ENSGALG00000012894
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrm2aENSDARG00000098612Danio rerio
 chrm2bENSDARG00000116374Danio rerio
 CHRM2ENSG00000181072Homo sapiens
 Chrm2ENSMUSG00000045613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRM4 / Gallus gallus cholinergic receptor muscarinic 4 (CHRM4), mRNA. / P08173* / P32211* / cholinergic receptor muscarinic 4*ENSGALG0000000836562
CHRM3 / muscarinic acetylcholine receptor M3 / P20309* / Q9ERZ3* / cholinergic receptor muscarinic 3* / cholinergic receptor, muscarinic 3, cardiac*ENSGALG0000001077845
CHRM5 / muscarinic acetylcholine receptor M5 / P08912* / Q920H4* / cholinergic receptor muscarinic 5*ENSGALG0000000964044
HRH1 / histamine receptor H1 / P35367* / P70174* / Histamine H1 receptor *ENSGALG0000000493026
HRH4 / histamine receptor H4 / Q91ZY2* / Q9H3N8* / Histamine H4 receptor *ENSGALG0000002609223
HRH3 / histamine receptor H3 / P58406* / Q9Y5N1* / Histamine H3 receptor *ENSGALG0000000517022
ENSGALG0000000442822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000995  Muscarinic acetylcholine receptor family
 IPR001065  Muscarinic acetylcholine receptor M2
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006940 regulation of smooth muscle contraction IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway IBA
 biological_processGO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway IBA
 biological_processGO:0007213 G-protein coupled acetylcholine receptor signaling pathway IEA
 biological_processGO:0007271 synaptic transmission, cholinergic IBA
 biological_processGO:0008016 regulation of heart contraction IBA
 biological_processGO:0009615 response to virus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016907 G-protein coupled acetylcholine receptor activity IBA
 molecular_functionGO:1990763 arrestin family protein binding IEA


Pathways (from Reactome)
Pathway description
Muscarinic acetylcholine receptors
G alpha (i) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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