ENSGALG00000012915


Gallus gallus

Features
Gene ID: ENSGALG00000012915
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : DNA replication licensing factor MCM4 / MCM4 / minichromosome maintenance complex component 4 / P33991 / P49717
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 108339012
Gene end: 108349903
  
Corresponding Affymetrix probe sets: Gga.7164.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021034
NCBI entrez gene - 426764     See in Manteia.
RefSeq - XM_424376
swissprot - E1C2U4
Ensembl - ENSGALG00000012915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcm4ENSDARG00000040041Danio rerio
 MCM4ENSG00000104738Homo sapiens
 Mcm4ENSMUSG00000022673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCM8 / I0IUP3 / DNA helicase MCM8 / Q9CWV1* / Q9UJA3* / minichromosome maintenance 8 homologous recombination repair factor*ENSGALG0000000919525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001208  MCM domain
 IPR003593  AAA+ ATPase domain
 IPR008047  Mini-chromosome maintenance complex protein 4
 IPR012340  Nucleic acid-binding, OB-fold
 IPR018525  Mini-chromosome maintenance, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027925  MCM N-terminal domain
 IPR031327  Mini-chromosome maintenance protein
 IPR033762  MCM OB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0042555 MCM complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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