ENSGALG00000012916


Gallus gallus

Features
Gene ID: ENSGALG00000012916
  
Biological name :DROSHA
  
Synonyms : DROSHA / ribonuclease 3
  
Possible biological names infered from orthology : drosha ribonuclease III / Q5HZJ0 / Q9NRR4
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 69434430
Gene end: 69503392
  
Corresponding Affymetrix probe sets: Gga.18715.1.A1_at (Chicken Array)   Gga.18715.1.S1_at (Chicken Array)   GgaAffx.12824.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021035
Ensembl peptide - ENSGALP00000042067
NCBI entrez gene - 420911     See in Manteia.
RefSeq - XM_015282183
RefSeq - NM_001006379
RefSeq - XM_015282182
RefSeq Peptide - NP_001006379
swissprot - R4GIX1
swissprot - F1NQC9
Ensembl - ENSGALG00000012916
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnasenENSDARG00000055563Danio rerio
 DROSHAENSG00000113360Homo sapiens
 DroshaENSMUSG00000022191Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000999  Ribonuclease III domain
 IPR011907  Ribonuclease III
 IPR014720  Double-stranded RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010586 miRNA metabolic process IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016075 rRNA catabolic process IEA
 biological_processGO:0030422 production of siRNA involved in RNA interference IBA
 biological_processGO:0031053 primary miRNA processing IBA
 biological_processGO:0031054 pre-miRNA processing IBA
 biological_processGO:0045589 regulation of regulatory T cell differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IBA
 biological_processGO:2000628 regulation of miRNA metabolic process IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0070877 microprocessor complex IEA
 molecular_functionGO:0001530 lipopolysaccharide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IBA
 molecular_functionGO:0004521 endoribonuclease activity IEA
 molecular_functionGO:0004525 ribonuclease III activity IBA
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046332 SMAD binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA
 molecular_functionGO:0070878 primary miRNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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